Gastroenterology
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1. Elsewhere in The AGA Journals (Preview Section)
2. Editorial Board
3. Table of Contents
4. Cover 1
5. AGA Living Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis Siddharth Singh, Edward V. Loftus, Berkeley N. Limketkai, John P. Haydek, Manasi Agrawal, Frank I. Scott, Ashwin N. Ananthakrishnan, AGA Clinical Guidelines Committee
6. CME Exam 1: An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk
7. Spotlight: Pharmacological Management of Moderate-to-Severe Ulcerative Colitis Siddharth Singh, Edward V. Loftus, Berkeley N. Limketkai, John P. Haydek, Manasi Agrawal, Frank I. Scott, Ashwin N. Ananthakrishnan, AGA Clinical Guidelines Committee
8. Gender Inequity in Pharma-Supported Inflammatory Bowel Disease Presentations: Shining a Light on Opportunities for Equality and Transparency in Medical Research Federica Di Vincenzo, Maria A. Quintero, Payton Mendygral, Maria T. Abreu
9. An Unusual Cause of Diarrhea and Hematochezia Siyu Chen, Quan Wen, Faming Zhang
10. A pan-genotypic hepatitis E virus replication inhibitor with high potency in a rat infection model Xin Zhang, Mara Klöhn, Sivi Ouwerkerk-Mahadevan, Michelle Jagst, Liesbeth Vereyken, Peter Verboven, Quinten Goovaerts, Daniel Todt, Tim H.M. Jonckers, Lotte Coelmont, Helen Fletcher, Kalyan Das, Kirandeep Samby, Johan Neyts, Eike Steinmann, Anil Koul, Suzanne J.F. Kaptein
11. Prevalence of Pediatric Inflammatory Bowel Disease in the United States: Pooled Estimates from Three Administrative Claims Data Sources Michael D. Kappelman, Colleen Brensinger, Lauren E. Parlett, Andres Hurtado-Lorenzo, James D. Lewis
12. Reply to Liang et al Alice Boilève, Michel Ducreux, Fanny Jaulin
13. PDO-Based Drug Screening in Advanced Pancreatic Cancer: Addressing Predictive Value and Broader Clinical Implications Chaojie Liang, Dan Shan, Zhigang Wei
14. Hypoxic and acidic tumor microenvironment-driven AVL9 promotes chemoresistance of pancreatic ductal adenocarcinoma via the AVL9-IκBα-SKP1 complex Jinsheng Ding, Yongjie Xie, Ziyun Liu, Zhaoyu Zhang, Bo Ni, Jingrui Yan, Tianxing Zhou, Jihui Hao
15. Expanding the Differential Diagnosis: Severe, Swollen Hepatocytes in a Patient with an ALT above 1000 U/L Michael Eller, Lindsey Westbrook, Avash Kalra
16. AGA Clinical Practice Update on Nonampullary Duodenal Lesions: Expert Review Michael J. Bourke, Simon K. Lo, Ross C.D. Buerlein, Koushik K. Das
17. AGA Clinical Practice Update on Endoscopic Enteral Access: Commentary Dejan Micic, John A. Martin, John Fang
18. High serum pesticide levels are associated with increased odds of inflammatory bowel disease in a nested case-control study Manasi Agrawal, Ryan C. Ungaro, Palak Rajauria, Jared Magee, Lauren Petrick, Vishal Midya, PREDICTS study collaborators
19. Sucrase isomaltase dysfunction reduces sucrose intake in mice and humans Peter Aldiss, Leire Torices, Stina Ramne, Marit Eika Jørgensen, Sucrase-Isomaltase Working Group, Mauro D’Amato, Mette K. Andersen
20. Exploring the Potential of Real-Time Audio-Visual Interactions of ChatGPT-4o in Endoscopy Training and Practice Qiqi Wu
21. An Unexpected Cause of Fistulizing Small Intestinal Disease Saam Dilmaghani, Rondell P. Graham, Seth Sweetser
22. CREEPING FAT-DERIVED FREE FATTY ACIDS INDUCE HYPERPLASIA OF INTESTINAL MUSCULARIS PROPRIA MUSCLE CELLS – A NOVEL LINK BETWEEN FAT AND INTESTINAL STRICTURE FORMATION IN CROHN’S DISEASE Weiwei Liu, Ren Mao, Thi Hong Nga Le, Gail West, Venkateshwari Varadharajan, Rakhee Banerjee, Genevieve Doyon, Pranab Mukherjee, Quang Tam Nguyen, Anny Mulya, Julie H. Rennison, Ilyssa O. Gordon, Michael Cruise, Shaomin Hu, Doug Czarnecki, Thomas Plesec, Jyotsna Chandra, Suhanti Banerjee, Jie Wang, William J. Massey, Idan Goren, Si-Nan Lin, Satya Kurada, Benjamin L. Cohen, Taha Qazi, Stefan D. Holubar, Jeremy Lipman, Arielle Kanters, Christy M. Gliniak, Philipp E. Scherer, Min-Hu Chen, Britta Siegmund, Andrei I. Ivanov, Claudio Fiocchi, David R. Van Wagoner, J. Mark Brown, Florian Rieder
23. Phase 3 validation of PAaM for hepatocellular carcinoma risk stratification in cirrhosis Naoto Fujiwara, Camden Lopez, Tracey L. Marsh, Indu Raman, Cesia A. Marquez, Subhojit Paul, Sumit K. Mishra, Naoto Kubota, Courtney Katz, Hiroaki Kanzaki, Michael Gonzalez, Lisa Quirk, Sneha Deodhar, Pratibha Selvakumar, Prithvi Raj, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex S. Befeler, Stephanie Page-Lester, Sudhir Srivastava, Ziding Feng, K. Rajender Reddy, Saira Khaderi, Sumeet K. Asrani, Fasiha Kanwal, Hashem B. El-Serag, Jorge A. Marrero, Amit G. Singal, Yujin Hoshida
24. Hacking Death in Dublin Seamus O'Mahony
25. A Rare Case of Enterocolitis with a Rare Cause Hirotaka Nakamura, Daisuke Watanabe, Yuzo Kodama
26. Adverse Events Associated with Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-analysis Kirles Bishay, Zhao Wu Meng, Rishad Khan, Mehul Gupta, Yibing Ruan, Marcus Vaska, Jordan Iannuzzi, Dylan E. O’Sullivan, Brittany Mah, Arun C.R. Partridge, Amanda M. Henderson, Howard Guo, Sunil Samnani, Max DeMarco, Yuhong Yuan, B. Joseph Elmunzer, Rajesh N. Keswani, Sachin Wani, Zachary L. Smith, Ronald J. Bridges, Steven J. Heitman, Robert J. Hilsden, Darren R. Brenner, Grigorios I. Leontiadis, Nauzer Forbes
27. An intriguing case of hepatosplenic lesions and pneumonia during anti-TNF therapy for IBD. Gabriel Luiz de Almeida Souza, Vinicius Andrade Chebli, Julio Maria Fonseca Chebli
28. Corrigendum
29. The new horizon of Clostridioides difficile infection treatment Ed.J. Kuijper, Kevin W. Garey
30. Comment on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Jixuan Wu, Zili Zhang, Lei Zhang
31. Comments on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Xian-Hui Zhang, Yang Liu, Yu-Xiang Gao, James Cheng-Chung Wei, Li-Yun Zhang
32. Reply Willemijn de Klaver, Manon van der Vlugt, Evelien Dekker
33. Re-evaluating Confounders and Risk Interpretation in FIT-Positive Cancer Screening Jiashu Han, Dan Shan
34. FIT-Positive Individuals: Is Timely Upper GI Endoscopy Necessary? Yunmeng Nie, Jianyu Lv, Junbin Yan
35. An Unusual Case of Gastric Multiple Lesions with Skin and Joint Abnormalities Haoran Jin, Feifan Chen, Jinlin Yang
36. Esophagogastroduodenoscopy for Positive Fecal Immunochemical Test Screeners? Much Done, More to Be Considered Lizhi Yi, Xiaoli Ren, Zhengyu Cheng
37. The Management of Internal Fistulizing Crohn’s Disease in a Child: More Than Meets the Eye Kelsey Jones, Luba Plotkin, Stavros Loukogeorgakis, Ruth Cytter-Kuint, Austen Worth, Dan Turner
38. A High-Resolution Microendoscope Improves Esophageal Cancer Screening and Surveillance: Implications for Underserved Global Settings Based on an International Randomized Controlled Trial Mimi C. Tan, Zhengqi Li, Kalpesh K. Patel, Fan Zhang, Xinying Yu, Xueshan Wang, Daniel G. Rosen, Sanford M. Dawsey, Liyan Xue, Chin Hur, Richard A. Schwarz, Imran Vohra, Yubo Tang, Mengfen Wu, Tao Wang, Jennifer Carns, Hong Xu, Rebecca R. Richards-Kortum, Guiqi Wang, Sharmila Anandasabapathy
39. Differing Epithelial and Immunologic Activation Patterns Following Food Reintroduction Reveal Different Transcriptional Profiles in Active Eosinophilic Esophagitis Ashley L. Pyne, Amiko M. Uchida, Mark W. Hazel, Maria A. Pletneva, Kristina Allen-Brady, Kathryn A. Peterson
40. Multi-cohort analysis reveals altered archaea in colorectal cancer fecal samples across populations Tianhui Li, Olabisi Oluwabukola Coker, Yang Sun, Shiyu Li, Chuanfa Liu, Yufeng Lin, Sunny H. Wong, Yinglei Miao, Joseph JY. Sung, Jun Yu
41. Reply Ingo Steinbrück
42. Evaluation of the Cold vs Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps in the German CHRONICLE Trial Yu Yang, Yaling Li, Chengzi Huang, Ting Yu, Jun Li
43. Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder Juan Pablo Arab, Alexandre Louvet, Maja Thiele, Gerald S. Winder, Robert J. Wong, Ashwani K. Singal
44. Detailed Information on Cold Snare Resection in Large Colorectal Polyps Koki Nakajima, Hiroaki Saito, Yoshitaka Nishikawa
45. Assessing the Preventative Effects of Vonoprazan Relative to Intravenous Proton Pump Inhibitors Following Endoscopic Intervention in Peptic Ulcers Wei-Zheng Tang, Tai-Hang Liu, Ying-Bo Li
46. Burn the Fat: Colon Cancer Tumors Are Skilled at Lipid Storage During Obesity Arianne L. Theiss, Christopher S. Williams
47. Faecalibacterium prausnitzii Is Associated With Clinical Response to Immune Checkpoint Inhibitors in Patients With Advanced Gastric Adenocarcinoma: Results of Microbiota Analysis of PRODIGE 59-FFCD 1707-DURIGAST Trial Marius Bredon, Karine Le Malicot, Christophe Louvet, Ludovic Evesque, Daniel Gonzalez, David Tougeron, Harry Sokol
48. Reply Tanawat Geeratragool, Uayporn Kaosombatwattana
49. Enhancing Cold Snare Endoscopic Mucosal Resection: Addressing Efficacy Concerns and Margin Management Jia Xu, Xiaowei Tang
50. CHRONICLE Trial: How Cool Is Cold Snaring for Endoscopic Mucosal Resection? Avinash Tiwari
51. Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis Ashwin N. Ananthakrishnan, M. Hassan Murad, Frank I. Scott, Manasi Agrawal, John P. Haydek, Berkeley N. Limketkai, Edward V. Loftus, Siddharth Singh
52. Methodology of Study on Glucagon-like Peptide-1 Receptor Agonists and Hepatocellular Carcinoma Risk James Cheng-Chung Wei, Poi Kuo, Qi Mei
53. Comments on “Association of GLP-1 Receptor Agonists and Hepatocellular Carcinoma Incidence and Hepatic Decompensation in Patients With Type 2 Diabetes” James Cheng-Chung Wei, Ching-Nung Wu, Wei-Chun Cheng
54. Evolutionary Medicine for Chronic Inflammatory Diseases of the Gut: More Than a Clinical Fantasy? Nadia Andrea Andreani, Daniel Unterweger, Stefan Schreiber, John F. Baines
55. A “How-to” Guide For Establishing an Effective Trainee Mentorship Program Kirstie Lithgow, Jordan Iannuzzi, Kelle Hurd, Suqing Li
56. Insights Into the Protective Role of GLP-1RAs in the Treatment of Type 2 Diabetes Mellitus: Implications for Hepatocellular Carcinoma and Hepatic Dysfunction Ziyi Wang, Jun Li, Yaling Li
57. Prospective Analysis of Liver Stiffness Measurement by Vibration Controlled Transient Elastography as a Predictor of Outcomes in Biliary Atresia Jean P. Molleston, Nathan P. Goodrich, Wen Ye, Daniel H. Leung, Ronald J. Sokol, Benjamin L. Shneider, Children Force Outcomes Working Group
58. GLP-1 Receptor Agonists' Role in Reducing Hepatocellular Carcinoma Risk Zaoqu Liu, Dan Shan, Xinwei Han
59. In Memoriam: Ikuo Hirano, MD Nirmala Gonsalves, Steven Flamm, Gary W. Falk, David A. Katzka
60. AGA Clinical Practice Update on Advances in Per-Oral Endoscopic Myotomy (POEM) and Remaining Questions—What We Have Learned in the Past Decade: Expert Review Dennis Yang, Robert Bechara, Christy M. Dunst, Vani J.A. Konda
61. Neurons on a Mission: Glial Global Positioning System for the Gut Reboot! Chalystha Yie Qin Lee, Kara Gross Margolis
62. Reply Rong Xu
63. Placebo Rates in Crohn’s Disease Randomized Clinical Trials: An Individual Patient Data Meta-analysis Virginia Solitano, Malcolm Hogan, Siddharth Singh, Silvio Danese, Laurent Peyrin-Biroulet, Guangyong Zou, Yuhong Yuan, Bruce E. Sands, Brian G. Feagan, Parambir S. Dulai, Neeraj Narula, Christopher Ma, Vipul Jairath
64. Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype) Malin Fromme, Audrey Payancé, Mattias Mandorfer, Katrine H. Thorhauge, Monica Pons, Marc Miravitlles, Jan Stolk, Bart van Hoek, Guido Stirnimann, Sona Frankova, Jan Sperl, Andreas E. Kremer, Barbara Burbaum, Christina Schrader, Amine Kadioglu, Michelle Walkenhaus, Carolin V. Schneider, Fabienne Klebingat, Lorenz Balcar, Naomi N. Kappe, Benedikt Schaefer, Joanna Chorostowska-Wynimko, Elmar Aigner, Sophie Gensluckner, Philipp Striedl, Pauline Roger, John Ryan, Suzanne Roche, Marius Vögelin, Aftab Ala, Heike Bantel, Jef Verbeek, Zoe Mariño, Michael Praktiknjo, Tom J.G. Gevers, Philipp A. Reuken, Thomas Berg, Jacob George, Münevver Demir, Tony Bruns, Christian Trautwein, Heinz Zoller, Michael Trauner, Joan Genesca, William J. Griffiths, Virginia Clark, Aleksander Krag, Alice M. Turner, Noel G. McElvaney, Pavel Strnad
65. Comparing the Performance of Commonly Used Fecal Immunochemical Tests Nauzer Forbes
66. Unveiling a Critical Role of IL-7 in Celiac Disease — Insights From a Novel Human Autoimmune Organoid Model Daniel Kotlarz
67. Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling Moeez Rathore, Kimberly Curry, Wei Huang, Michel’le Wright, Daniel Martin, Jiyeon Baek, Derek Taylor, Masaru Miyagi, Wen Tang, Hao Feng, Yamu Li, Zhenghe Wang, Hallie Graor, Joseph Willis, Elizabeth Bryson, Christina S. Boutros, Omkar Desai, Bianca Islam, Lee M. Ellis, Stephen E. Moss, Jordan M. Winter, John Greenwood, Rui Wang
68. Eosinophils Are Just the Tip of the Iceberg for Eosinophilic Esophagitis Eric E. Low, Rena Yadlapati
69. The First Approved Therapy in Infants and Young Children With EoE — Now the Big Question: Where Will Dupilumab Fit Into Real-World Practice? Eric E. Low, Rena Yadlapati
70. Immune Checkpoint Inhibitor–Induced Colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
71. Persistent Severe Abdominal Pain in a 40-Year-Old Male Patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
72. Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
73. Novel Immune Manipulators for IBD: Miniproteins! Eytan Wine
74. Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium, Maria Abreu, Paul Beck, Charles Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Anne Griffiths, David Guttman, Kevan Jacobson, Gilaad Kaplan, Denis O. Krause, Karen Madsen, John Marshall, Paul Moayyedi, Mark Ropeleski, Ernest Seidman, Mark Silverberg, Scott Snapper, Andy Stadnyk, A. Hillary Steinhart, Michael Surette, Dan Turner, Thomas Walters, Bruce Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee Denson, Colette Deslandres, Wael El-Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David Mack, Jerry McGrath, Anthony Otley, Remo Panancionne, Maria Abreu, Guy Aumais, Robert Baldassano, Charles Bernstein, Maria Cino, Lee Denson, Colette Deslandres, Wael El-Matary, Anne M. Griffiths, Charlotte Hedin, Hans Herfarth, Peter Higgins, Seamus Hussey, Hien Q. Huynh, Kevan Jacobson, David Keljo, David Kevans, Charlie Lees, David Mack, John Marshall, Jerry McGrath, Sanjay Murthy, Anthony Otley, Remo Panaccione, Nimisha Parekh, Sophie Plamondon, Graham Radford-Smith, Mark Ropeleski, Joel Rosh, David Rubin, Michael Schultz, Ernest Seidman, Corey Siegel, Scott Snapper, A. Hillary Steinhart, Dan Turner
75. The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
76. Use of Large Language Models to Identify Surveillance Colonoscopy Intervals—A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
77. Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nachef, Paul Feuerstadt, Thomas J. Borody, Sahil Khanna, Shrish Budree, Zain Kassam
78. Hidden Footprints in Ascites: Lessons From a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
79. Corrigendum
80. Surveillance for Hepatocellular Carcinoma in Cirrhosis: End of Monopoly for Serum Alpha Fetoprotein Lung-Yi Mak, Man-Fung Yuen
81. A Brain-Gut Pathway for Stress-Induced Microbiome Change Sarah A. Najjar, Kara Gross Margolis
82. Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler, Elena Sonnenberg, Michael Schumann, Lea-Maxie Haag, Dieter Beule, Lukas Flatz, TRR241 IBDome Consortium, Zlatko Trjanoski, Geert D’Haens, Carl Weidinger, Henrik E. Mei, Britta Siegmund, Kevin Thurley, Ahmed N. Hegazy
83. The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
84. It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About Inflammatory Bowel Disease Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
85. Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
86. Reply Fernando Azpiroz
87. Reply Hanseul Kim, Long H. Nguyen
88. Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
89. Focus on Psychological Intervention: Insights from Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention Chenhong Tian, Changlin Zhai, Haihua Pan
90. Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren
91. Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
92. Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
93. Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
94. Interventions for Improving Quality of Colonoscopy Qing-hua Wang, Min Zhang, Hua Chen, Wei Han
95. Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
96. Detection of Gastrointestinal Bleeding With Large Language Models to Aid Quality Improvement and Appropriate Reimbursement Neil S. Zheng, Vipina K. Keloth, Kisung You, Daniel Kats, Darrick K. Li, Ohm Deshpande, Hamita Sachar, Hua Xu, Loren Laine, Dennis L. Shung
97. Obesity-Facilitated Colon Cancer Progression Is Mediated by Increased Diacylglycerol O-Acyltransferases 1 and 2 Levels Jenisha Ghimire, Morgan E. Collins, Patricia Snarski, Angelle N. King, Emmanuelle Ruiz, Rida Iftikhar, Harrison M. Penrose, Krzysztof Moroz, Tyler Rorison, Melody Baddoo, Muhammad Anas Naeem, Arnold H. Zea, Scott T. Magness, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
98. Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells Sarah A. Dooley, Elena Kolobova, Andreanna Burman, Izumi Kaji, Jessica R. Digrazia, Rachel Stubler, Anna Goldstein, Charulekha Packirisamy, Alexander W. Coutts, Milena Saqui-Salces, Nan Gao, Melinda A. Engevik, Mitchell D. Shub, James R. Goldenring, Amy C. Engevik
99. A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex Befeler, Stephanie Page-Lester, Nabihah Tayob, Sudhir Srivastava, Jo Ann Rinaudo, Amit G. Singal, K. Rajender Reddy, Jorge A. Marrero
100. Reply Timothy B. Gardner, Walter G. Park, Peter J. Allen
更新于 46 分钟前

近期历史最近 100 条记录

2024-11-23 A pan-genotypic hepatitis E virus replication inhibitor with high potency in a rat infection model Xin Zhang, Mara Klöhn, Sivi Ouwerkerk-Mahadevan, Michelle Jagst, Liesbeth Vereyken, Peter Verboven, Quinten Goovaerts, Daniel Todt, Tim H.M. Jonckers, Lotte Coelmont, Helen Fletcher, Kalyan Das, Kirandeep Samby, Johan Neyts, Eike Steinmann, Anil Koul, Suz
2024-11-23 An Unusual Cause of Diarrhea and Hematochezia Siyu Chen, Quan Wen, Faming Zhang
2024-11-20 Prevalence of Pediatric Inflammatory Bowel Disease in the United States: Pooled Estimates from Three Administrative Claims Data Sources Michael D. Kappelman, Colleen Brensinger, Lauren E. Parlett, Andres Hurtado-Lorenzo, James D. Lewis
2024-11-19 Reply to Liang et al Alice Boilève, Michel Ducreux, Fanny Jaulin
2024-11-19 PDO-Based Drug Screening in Advanced Pancreatic Cancer: Addressing Predictive Value and Broader Clinical Implications Chaojie Liang, Dan Shan, Zhigang Wei
2024-11-19 Elsewhere in The AGA Journals (Preview Section)
2024-11-19 Editorial Board
2024-11-19 Table of Contents
2024-11-19 Cover 1
2024-11-19 AGA Living Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis Siddharth Singh, Edward V. Loftus, Berkeley N. Limketkai, John P. Haydek, Manasi Agrawal, Frank I. Scott, Ashwin N. Ananthakrishnan, AGA Clinical Guidelines Committee
2024-11-19 CME Exam 1: An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk
2024-11-19 Spotlight: Pharmacological Management of Moderate-to-Severe Ulcerative Colitis Siddharth Singh, Edward V. Loftus, Berkeley N. Limketkai, John P. Haydek, Manasi Agrawal, Frank I. Scott, Ashwin N. Ananthakrishnan, AGA Clinical Guidelines Committee
2024-11-19 Gender Inequity in Pharma-Supported Inflammatory Bowel Disease Presentations: Shining a Light on Opportunities for Equality and Transparency in Medical Research Federica Di Vincenzo, Maria A. Quintero, Payton Mendygral, Maria T. Abreu
2024-11-19 Hypoxic and acidic tumor microenvironment-driven AVL9 promotes chemoresistance of pancreatic ductal adenocarcinoma via the AVL9-IκBα-SKP1 complex Jinsheng Ding, Yongjie Xie, Ziyun Liu, Zhaoyu Zhang, Bo Ni, Jingrui Yan, Tianxing Zhou, Jihui Hao
2024-11-16 Expanding the Differential Diagnosis: Severe, Swollen Hepatocytes in a Patient with an ALT above 1000 U/L Michael Eller, Lindsey Westbrook, Avash Kalra
2024-11-16 AGA Clinical Practice Update on Nonampullary Duodenal Lesions: Expert Review Michael J. Bourke, Simon K. Lo, Ross C.D. Buerlein, Koushik K. Das
2024-11-15 AGA Clinical Practice Update on Endoscopic Enteral Access: Commentary Dejan Micic, John A. Martin, John Fang
2024-11-15 High serum pesticide levels are associated with increased odds of inflammatory bowel disease in a nested case-control study Manasi Agrawal, Ryan C. Ungaro, Palak Rajauria, Jared Magee, Lauren Petrick, Vishal Midya, PREDICTS study collaborators
2024-11-13 Sucrase isomaltase dysfunction reduces sucrose intake in mice and humans Peter Aldiss, Leire Torices, Stina Ramne, Marit Eika Jørgensen, Sucrase-Isomaltase Working Group, Mauro D’Amato, Mette K. Andersen
2024-11-12 Exploring the Potential of Real-Time Audio-Visual Interactions of ChatGPT-4o in Endoscopy Training and Practice Qiqi Wu
2024-11-09 An Unexpected Cause of Fistulizing Small Intestinal Disease Saam Dilmaghani, Rondell P. Graham, Seth Sweetser
2024-11-08 CREEPING FAT-DERIVED FREE FATTY ACIDS INDUCE HYPERPLASIA OF INTESTINAL MUSCULARIS PROPRIA MUSCLE CELLS – A NOVEL LINK BETWEEN FAT AND INTESTINAL STRICTURE FORMATION IN CROHN’S DISEASE Weiwei Liu, Ren Mao, Thi Hong Nga Le, Gail West, Venkateshwari Varadharajan, Rakhee Banerjee, Genevieve Doyon, Pranab Mukherjee, Quang Tam Nguyen, Anny Mulya, Julie H. Rennison, Ilyssa O. Gordon, Michael Cruise, Shaomin Hu, Doug Czarnecki, Thomas Plesec,
2024-11-08 Phase 3 validation of PAaM for hepatocellular carcinoma risk stratification in cirrhosis Naoto Fujiwara, Camden Lopez, Tracey L. Marsh, Indu Raman, Cesia A. Marquez, Subhojit Paul, Sumit K. Mishra, Naoto Kubota, Courtney Katz, Hiroaki Kanzaki, Michael Gonzalez, Lisa Quirk, Sneha Deodhar, Pratibha Selvakumar, Prithvi Raj, Neehar D. Parikh, Lew
2024-11-07 Hacking Death in Dublin Seamus O'Mahony
2024-11-07 Corrigendum
2024-11-07 An intriguing case of hepatosplenic lesions and pneumonia during anti-TNF therapy for IBD. Gabriel Luiz de Almeida Souza, Vinicius Andrade Chebli, Julio Maria Fonseca Chebli
2024-11-07 A Rare Case of Enterocolitis with a Rare Cause Hirotaka Nakamura, Daisuke Watanabe, Yuzo Kodama
2024-11-07 Adverse Events Associated with Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-analysis Kirles Bishay, Zhao Wu Meng, Rishad Khan, Mehul Gupta, Yibing Ruan, Marcus Vaska, Jordan Iannuzzi, Dylan E. O’Sullivan, Brittany Mah, Arun C.R. Partridge, Amanda M. Henderson, Howard Guo, Sunil Samnani, Max DeMarco, Yuhong Yuan, B. Joseph Elmunzer, Rajesh
2024-11-05 The new horizon of Clostridioides difficile infection treatment Ed.J. Kuijper, Kevin W. Garey
2024-11-02 Comments on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Xian-Hui Zhang, Yang Liu, Yu-Xiang Gao, James Cheng-Chung Wei, Li-Yun Zhang
2024-11-02 Esophagogastroduodenoscopy for Positive Fecal Immunochemical Test Screeners? Much Done, More to Be Considered Lizhi Yi, Xiaoli Ren, Zhengyu Cheng
2024-11-02 FIT-Positive Individuals: Is Timely Upper GI Endoscopy Necessary? Yunmeng Nie, Jianyu Lv, Junbin Yan
2024-11-01 Comment on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Jixuan Wu, Zili Zhang, Lei Zhang
2024-11-01 Re-evaluating Confounders and Risk Interpretation in FIT-Positive Cancer Screening Jiashu Han, Dan Shan
2024-11-01 An Unusual Case of Gastric Multiple Lesions with Skin and Joint Abnormalities Haoran Jin, Feifan Chen, Jinlin Yang
2024-11-01 Reply Willemijn de Klaver, Manon van der Vlugt, Evelien Dekker
2024-10-29 The Management of Internal Fistulizing Crohn’s Disease in a Child: More Than Meets the Eye Kelsey Jones, Luba Plotkin, Stavros Loukogeorgakis, Ruth Cytter-Kuint, Austen Worth, Dan Turner
2024-10-29 A High-Resolution Microendoscope Improves Esophageal Cancer Screening and Surveillance: Implications for Underserved Global Settings Based on an International Randomized Controlled Trial Mimi C. Tan, Zhengqi Li, Kalpesh K. Patel, Fan Zhang, Xinying Yu, Xueshan Wang, Daniel G. Rosen, Sanford M. Dawsey, Liyan Xue, Chin Hur, Richard A. Schwarz, Imran Vohra, Yubo Tang, Mengfen Wu, Tao Wang, Jennifer Carns, Hong Xu, Rebecca R. Richards-Kortum,
2024-10-26 Differing Epithelial and Immunologic Activation Patterns Following Food Reintroduction Reveal Different Transcriptional Profiles in Active Eosinophilic Esophagitis Ashley L. Pyne, Amiko M. Uchida, Mark W. Hazel, Maria A. Pletneva, Kristina Allen-Brady, Kathryn A. Peterson
2024-10-26 Multi-cohort analysis reveals altered archaea in colorectal cancer fecal samples across populations Tianhui Li, Olabisi Oluwabukola Coker, Yang Sun, Shiyu Li, Chuanfa Liu, Yufeng Lin, Sunny H. Wong, Yinglei Miao, Joseph JY. Sung, Jun Yu
2024-10-25 Reply Ingo Steinbrück
2024-10-25 Evaluation of the Cold vs Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps in the German CHRONICLE Trial Yu Yang, Yaling Li, Chengzi Huang, Ting Yu, Jun Li
2024-10-24 Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder Juan Pablo Arab, Alexandre Louvet, Maja Thiele, Gerald S. Winder, Robert J. Wong, Ashwani K. Singal
2024-10-23 Faecalibacterium prausnitzii Is Associated With Clinical Response to Immune Checkpoint Inhibitors in Patients With Advanced Gastric Adenocarcinoma: Results of Microbiota Analysis of PRODIGE 59-FFCD 1707-DURIGAST Trial Marius Bredon, Karine Le Malicot, Christophe Louvet, Ludovic Evesque, Daniel Gonzalez, David Tougeron, Harry Sokol
2024-10-23 Burn the Fat: Colon Cancer Tumors Are Skilled at Lipid Storage During Obesity Arianne L. Theiss, Christopher S. Williams
2024-10-23 Detailed Information on Cold Snare Resection in Large Colorectal Polyps Koki Nakajima, Hiroaki Saito, Yoshitaka Nishikawa
2024-10-23 Reply Tanawat Geeratragool, Uayporn Kaosombatwattana
2024-10-23 Assessing the Preventative Effects of Vonoprazan Relative to Intravenous Proton Pump Inhibitors Following Endoscopic Intervention in Peptic Ulcers Wei-Zheng Tang, Tai-Hang Liu, Ying-Bo Li
2024-10-22 CHRONICLE Trial: How Cool Is Cold Snaring for Endoscopic Mucosal Resection? Avinash Tiwari
2024-10-21 Enhancing Cold Snare Endoscopic Mucosal Resection: Addressing Efficacy Concerns and Margin Management Jia Xu, Xiaowei Tang
2024-10-19 Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis Ashwin N. Ananthakrishnan, M. Hassan Murad, Frank I. Scott, Manasi Agrawal, John P. Haydek, Berkeley N. Limketkai, Edward V. Loftus, Siddharth Singh
2024-10-18 Table of Contents
2024-10-18 Cover 1
2024-10-18 Editorial Board
2024-10-18 Elsewhere in The AGA Journals (Preview Section)
2024-10-18 Disparities in Gastrointestinal Health for US Immigrant Populations, and Strategies to Address These Disparities Miguel Malespin, Saikiran M. Kilaru
2024-10-18 CME Exam 1: Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies
2024-10-18 Prospective Analysis of Liver Stiffness Measurement by Vibration Controlled Transient Elastography as a Predictor of Outcomes in Biliary Atresia Jean P. Molleston, Nathan P. Goodrich, Wen Ye, Daniel H. Leung, Ronald J. Sokol, Benjamin L. Shneider, Children Force Outcomes Working Group
2024-10-18 Comments on “Association of GLP-1 Receptor Agonists and Hepatocellular Carcinoma Incidence and Hepatic Decompensation in Patients With Type 2 Diabetes” James Cheng-Chung Wei, Ching-Nung Wu, Wei-Chun Cheng
2024-10-18 Methodology of Study on Glucagon-like Peptide-1 Receptor Agonists and Hepatocellular Carcinoma Risk James Cheng-Chung Wei, Poi Kuo, Qi Mei
2024-10-18 Evolutionary Medicine for Chronic Inflammatory Diseases of the Gut: More Than a Clinical Fantasy? Nadia Andrea Andreani, Daniel Unterweger, Stefan Schreiber, John F. Baines
2024-10-18 Insights Into the Protective Role of GLP-1RAs in the Treatment of Type 2 Diabetes Mellitus: Implications for Hepatocellular Carcinoma and Hepatic Dysfunction Ziyi Wang, Jun Li, Yaling Li
2024-10-17 A “How-to” Guide For Establishing an Effective Trainee Mentorship Program Kirstie Lithgow, Jordan Iannuzzi, Kelle Hurd, Suqing Li
2024-10-17 GLP-1 Receptor Agonists' Role in Reducing Hepatocellular Carcinoma Risk Zaoqu Liu, Dan Shan, Xinwei Han
2024-10-17 In Memoriam: Ikuo Hirano, MD Nirmala Gonsalves, Steven Flamm, Gary W. Falk, David A. Katzka
2024-10-17 AGA Clinical Practice Update on Advances in Per-Oral Endoscopic Myotomy (POEM) and Remaining Questions—What We Have Learned in the Past Decade: Expert Review Dennis Yang, Robert Bechara, Christy M. Dunst, Vani J.A. Konda
2024-10-16 Reply Rong Xu
2024-10-16 Neurons on a Mission: Glial Global Positioning System for the Gut Reboot! Chalystha Yie Qin Lee, Kara Gross Margolis
2024-10-15 Placebo Rates in Crohn’s Disease Randomized Clinical Trials: An Individual Patient Data Meta-analysis Virginia Solitano, Malcolm Hogan, Siddharth Singh, Silvio Danese, Laurent Peyrin-Biroulet, Guangyong Zou, Yuhong Yuan, Bruce E. Sands, Brian G. Feagan, Parambir S. Dulai, Neeraj Narula, Christopher Ma, Vipul Jairath
2024-10-15 Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype) Malin Fromme, Audrey Payancé, Mattias Mandorfer, Katrine H. Thorhauge, Monica Pons, Marc Miravitlles, Jan Stolk, Bart van Hoek, Guido Stirnimann, Sona Frankova, Jan Sperl, Andreas E. Kremer, Barbara Burbaum, Christina Schrader, Amine Kadioglu, Michelle Wa
2024-10-14 Unveiling a Critical Role of IL-7 in Celiac Disease — Insights From a Novel Human Autoimmune Organoid Model Daniel Kotlarz
2024-10-14 Comparing the Performance of Commonly Used Fecal Immunochemical Tests Nauzer Forbes
2024-10-10 Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling Moeez Rathore, Kimberly Curry, Wei Huang, Michel’le Wright, Daniel Martin, Jiyeon Baek, Derek Taylor, Masaru Miyagi, Wen Tang, Hao Feng, Yamu Li, Zhenghe Wang, Hallie Graor, Joseph Willis, Elizabeth Bryson, Christina S. Boutros, Omkar Desai, Bianca Islam,
2024-10-09 Eosinophils Are Just the Tip of the Iceberg for Eosinophilic Esophagitis Eric E. Low, Rena Yadlapati
2024-10-09 The First Approved Therapy in Infants and Young Children With EoE — Now the Big Question: Where Will Dupilumab Fit Into Real-World Practice? Eric E. Low, Rena Yadlapati
2024-10-09 Persistent Severe Abdominal Pain in a 40-Year-Old Male Patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
2024-10-09 Novel Immune Manipulators for IBD: Miniproteins! Eytan Wine
2024-10-09 Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
2024-10-08 Immune Checkpoint Inhibitor–Induced Colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
2024-10-08 Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium, Maria Abreu, Paul Beck, Charles Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Ann
2024-10-03 The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
2024-10-02 Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nac
2024-10-02 Use of Large Language Models to Identify Surveillance Colonoscopy Intervals—A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
2024-10-01 Hidden Footprints in Ascites: Lessons From a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
2024-10-01 Corrigendum
2024-09-28 Surveillance for Hepatocellular Carcinoma in Cirrhosis: End of Monopoly for Serum Alpha Fetoprotein Lung-Yi Mak, Man-Fung Yuen
2024-09-28 A Brain-Gut Pathway for Stress-Induced Microbiome Change Sarah A. Najjar, Kara Gross Margolis
2024-09-28 Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Li
2024-09-26 It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About Inflammatory Bowel Disease Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
2024-09-26 The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
2024-09-21 Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
2024-09-21 Reply Fernando Azpiroz
2024-09-21 Reply Hanseul Kim, Long H. Nguyen
2024-09-21 Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
2024-09-20 Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
2024-09-20 Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
2024-09-20 Interventions for Improving Quality of Colonoscopy Qing-hua Wang, Min Zhang, Hua Chen, Wei Han
2024-09-20 Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
2024-09-20 Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
2024-09-20 Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren

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