Gastroenterology
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1. Sucrase isomaltase dysfunction reduces sucrose intake in mice and humans Peter Aldiss, Leire Torices, Stina Ramne, Marit Eika Jørgensen, Sucrase-Isomaltase Working Group, Mauro D’Amato, Mette K. Andersen
2. Exploring the Potential of Real-Time Audio-Visual Interactions of ChatGPT-4o in Endoscopy Training and Practice Qiqi Wu
3. CREEPING FAT-DERIVED FREE FATTY ACIDS INDUCE HYPERPLASIA OF INTESTINAL MUSCULARIS PROPRIA MUSCLE CELLS – A NOVEL LINK BETWEEN FAT AND INTESTINAL STRICTURE FORMATION IN CROHN’S DISEASE Weiwei Liu, Ren Mao, Thi Hong Nga Le, Gail West, Venkateshwari Varadharajan, Rakhee Banerjee, Genevieve Doyon, Pranab Mukherjee, Quang Tam Nguyen, Anny Mulya, Julie H. Rennison, Ilyssa O. Gordon, Michael Cruise, Shaomin Hu, Doug Czarnecki, Thomas Plesec, Jyotsna Chandra, Suhanti Banerjee, Jie Wang, William J. Massey, Idan Goren, Si-Nan Lin, Satya Kurada, Benjamin L. Cohen, Taha Qazi, Stefan D. Holubar, Jeremy Lipman, Arielle Kanters, Christy M. Gliniak, Philipp E. Scherer, Min-Hu Chen, Britta Siegmund, Andrei I. Ivanov, Claudio Fiocchi, David R. Van Wagoner, J. Mark Brown, Florian Rieder
4. An Unexpected Cause of Fistulizing Small Intestinal Disease Saam Dilmaghani, Rondell P. Graham, Seth Sweetser
5. Phase 3 validation of PAaM for hepatocellular carcinoma risk stratification in cirrhosis Naoto Fujiwara, Camden Lopez, Tracey L. Marsh, Indu Raman, Cesia A. Marquez, Subhojit Paul, Sumit K. Mishra, Naoto Kubota, Courtney Katz, Hiroaki Kanzaki, Michael Gonzalez, Lisa Quirk, Sneha Deodhar, Pratibha Selvakumar, Prithvi Raj, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex S. Befeler, Stephanie Page-Lester, Sudhir Srivastava, Ziding Feng, K. Rajender Reddy, Saira Khaderi, Sumeet K. Asrani, Fasiha Kanwal, Hashem B. El-Serag, Jorge A. Marrero, Amit G. Singal, Yujin Hoshida
6. Corrigendum
7. Adverse Events Associated with Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-analysis Kirles Bishay, Zhao Wu Meng, Rishad Khan, Mehul Gupta, Yibing Ruan, Marcus Vaska, Jordan Iannuzzi, Dylan E. O’Sullivan, Brittany Mah, Arun C.R. Partridge, Amanda M. Henderson, Howard Guo, Sunil Samnani, Max DeMarco, Yuhong Yuan, B. Joseph Elmunzer, Rajesh N. Keswani, Sachin Wani, Zachary L. Smith, Ronald J. Bridges, Steven J. Heitman, Robert J. Hilsden, Darren R. Brenner, Grigorios I. Leontiadis, Nauzer Forbes
8. An intriguing case of hepatosplenic lesions and pneumonia during anti-TNF therapy for IBD. Gabriel Luiz de Almeida Souza, Vinicius Andrade Chebli, Julio Maria Fonseca Chebli
9. A Rare Case of Enterocolitis with a Rare Cause Hirotaka Nakamura, Daisuke Watanabe, Yuzo Kodama
10. Hacking Death in Dublin Seamus O'Mahony
11. The new horizon of Clostridioides difficile infection treatment Ed.J. Kuijper, Kevin W. Garey
12. FIT-positive individuals: is timely upper GI endoscopy necessary? Yunmeng Nie, Jianyu Lv, Junbin Yan
13. Comments on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Xian-hui Zhang, Yang Liu, Yu-xiang Gao, James Cheng-Chung Wei, Li-yun Zhang
14. Esophagogastroduodenoscopy for Positive Fecal Immunochemical Test Screeners? Much Done, More to Be Considered. Lizhi Yi, Xiaoli Ren, Zhengyu Cheng
15. Comment on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Jixuan Wu, Zili Zhang, Lei Zhang
16. Reevaluating Confounders and Risk Interpretation in FIT-Positive Cancer Screening Jiashu Han, Dan Shan
17. Reply to Nie et al, Zhang et al, Yi et al, Wu et al, and Han andShan Willemijn de Klaver, Manon van der Vlugt, Evelien Dekker
18. An Unusual Case of Gastric Multiple Lesions with Skin and Joint Abnormalities Haoran Jin, Feifan Chen, Jinlin Yang
19. CME Exam 1: Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies
20. Cover 1
21. Editorial Board
22. Disparities in Gastrointestinal Health for US Immigrant Populations, and Strategies to Address These Disparities Miguel Malespin, Saikiran M. Kilaru
23. Table of Contents
24. Elsewhere in The AGA Journals (Preview Section)
25. A HIGH-RESOLUTION MICROENDOSCOPE IMPROVES ESOPHAGEAL CANCER SCREENING AND SURVEILLANCE: IMPLICATIONS FOR UNDERSERVED GLOBAL SETTINGS BASED ON AN INTERNATIONAL, RANDOMIZED CONTROLLED TRIAL Mimi C. Tan, Zhengqi Li, Kalpesh K. Patel, Fan Zhang, Xinying Yu, Xueshan Wang, Daniel G. Rosen, Sanford M. Dawsey, Liyan Xue, Chin Hur, Richard A. Schwarz, Imran Vohra, Yubo Tang, Mengfen Wu, Tao Wang, Jennifer Carns, Hong Xu, Rebecca R. Richards-Kortum, Guiqi Wang, Sharmila Anandasabapathy
26. The management of internal fistulizing Crohn’s disease in a child: more than meets the eye Kelsey Jones, Luba Plotkin, Stavros Loukogeorgakis, Ruth Cytter-Kuint, Austen Worth, Dan Turner
27. Differing Epithelial and Immunologic Activation Patterns Following Food Reintroduction Reveal Different Transcriptional Profiles in Active Eosinophilic Esophagitis Ashley L. Pyne, Amiko M. Uchida, Mark W. Hazel, Maria A. Pletneva, Kristina Allen-Brady, Kathryn A. Peterson
28. Multi-cohort analysis reveals altered archaea in colorectal cancer fecal samples across populations Tianhui Li, Olabisi Oluwabukola Coker, Yang Sun, Shiyu Li, Chuanfa Liu, Yufeng Lin, Sunny H. Wong, Yinglei Miao, Joseph JY. Sung, Jun Yu
29. Reply Ingo Steinbrück
30. Evaluation of the Cold Versus Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps in the German CHRONICLE Trial Yu Yang, Yaling Li, Chengzi Huang, Ting Yu, Jun Li
31. Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder Juan Pablo Arab, Alexandre Louvet, Maja Thiele, Gerald S. Winder, Robert J. Wong, Ashwani K. Singal
32. Detailed Information on Cold Snare Resection in Large Colorectal Polyps Koki Nakajima, Hiroaki Saito, Yoshitaka Nishikawa
33. Assessing the Preventative Effects of Vonoprazan Relative to Intravenous Proton Pump Inhibitors Following Endoscopic Intervention in Peptic Ulcers Wei-Zheng Tang, Tai-Hang Liu, Ying-Bo Li
34. Reply Tanawat Geeratragool, Uayporn Kaosombatwattana
35. Faecalibacterium prausnitzii Is Associated With Clinical Response to Immune Checkpoint Inhibitors in Patients With Advanced Gastric Adenocarcinoma: Results of Microbiota Analysis of PRODIGE 59-FFCD 1707-DURIGAST Trial Marius Bredon, Karine Le Malicot, Christophe Louvet, Ludovic Evesque, Daniel Gonzalez, David Tougeron, Harry Sokol
36. Burn the Fat: Colon Cancer Tumors Are Skilled at Lipid Storage During Obesity Arianne L. Theiss, Christopher S. Williams
37. CHRONICLE Trial: How Cool Is Cold Snaring for Endoscopic Mucosal Resection? Avinash Tiwari
38. Enhancing Cold Snare Endoscopic Mucosal Resection: Addressing Efficacy Concerns and Margin Management Jia Xu, Xiaowei Tang
39. Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis Ashwin N. Ananthakrishnan, M. Hassan Murad, Frank I. Scott, Manasi Agrawal, John P. Haydek, Berkeley N. Limketkai, Edward V. Loftus, Siddharth Singh
40. Prospective Analysis of Liver Stiffness Measurement by Vibration Controlled Transient Elastography as a Predictor of Outcomes in Biliary Atresia Jean P. Molleston, Nathan P. Goodrich, Wen Ye, Daniel H. Leung, Ronald J. Sokol, Benjamin L. Shneider, Children Force Outcomes Working Group
41. A “How-to” Guide For Establishing an Effective Trainee Mentorship Program Kirstie Lithgow, Jordan Iannuzzi, Kelle Hurd, Suqing Li
42. Insights Into the Protective Role of GLP-1RAs in the Treatment of Type 2 Diabetes Mellitus: Implications for Hepatocellular Carcinoma and Hepatic Dysfunction Ziyi Wang, Jun Li, Yaling Li
43. Methodology of Study on Glucagon-like Peptide-1 Receptor Agonists and Hepatocellular Carcinoma Risk James Cheng-Chung Wei, Poi Kuo, Qi Mei
44. Comments on “Association of GLP-1 Receptor Agonists and Hepatocellular Carcinoma Incidence and Hepatic Decompensation in Patients With Type 2 Diabetes” James Cheng-Chung Wei, Ching-Nung Wu, Wei-Chun Cheng
45. Evolutionary Medicine for Chronic Inflammatory Diseases of the Gut: More Than a Clinical Fantasy? Nadia Andrea Andreani, Daniel Unterweger, Stefan Schreiber, John F. Baines
46. GLP-1 Receptor Agonists' Role in Reducing Hepatocellular Carcinoma Risk Zaoqu Liu, Dan Shan, Xinwei Han
47. AGA Clinical Practice Update on Advances in Per-Oral Endoscopic Myotomy (POEM) and Remaining Questions—What We Have Learned in the Past Decade: Expert Review Dennis Yang, Robert Bechara, Christy M. Dunst, Vani J.A. Konda
48. In Memoriam: Ikuo Hirano, MD Nirmala Gonsalves, Steven Flamm, Gary W. Falk, David A. Katzka
49. Reply Rong Xu
50. Neurons on a Mission: Glial Global Positioning System for the Gut Reboot! Chalystha Yie Qin Lee, Kara Gross Margolis
51. Placebo Rates in Crohn’s Disease Randomized Clinical Trials: An Individual Patient Data Meta-analysis Virginia Solitano, Malcolm Hogan, Siddharth Singh, Silvio Danese, Laurent Peyrin-Biroulet, Guangyong Zou, Yuhong Yuan, Bruce E. Sands, Brian G. Feagan, Parambir S. Dulai, Neeraj Narula, Christopher Ma, Vipul Jairath
52. Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype) Malin Fromme, Audrey Payancé, Mattias Mandorfer, Katrine H. Thorhauge, Monica Pons, Marc Miravitlles, Jan Stolk, Bart van Hoek, Guido Stirnimann, Sona Frankova, Jan Sperl, Andreas E. Kremer, Barbara Burbaum, Christina Schrader, Amine Kadioglu, Michelle Walkenhaus, Carolin V. Schneider, Fabienne Klebingat, Lorenz Balcar, Naomi N. Kappe, Benedikt Schaefer, Joanna Chorostowska-Wynimko, Elmar Aigner, Sophie Gensluckner, Philipp Striedl, Pauline Roger, John Ryan, Suzanne Roche, Marius Vögelin, Aftab Ala, Heike Bantel, Jef Verbeek, Zoe Mariño, Michael Praktiknjo, Tom J.G. Gevers, Philipp A. Reuken, Thomas Berg, Jacob George, Münevver Demir, Tony Bruns, Christian Trautwein, Heinz Zoller, Michael Trauner, Joan Genesca, William J. Griffiths, Virginia Clark, Aleksander Krag, Alice M. Turner, Noel G. McElvaney, Pavel Strnad
53. Unveiling a Critical Role of IL-7 in Celiac Disease — Insights From a Novel Human Autoimmune Organoid Model Daniel Kotlarz
54. Comparing the Performance of Commonly Used Fecal Immunochemical Tests Nauzer Forbes
55. Eosinophils Are Just the Tip of the Iceberg for Eosinophilic Esophagitis Eric E. Low, Rena Yadlapati
56. The First Approved Therapy in Infants and Young Children With EoE — Now the Big Question: Where Will Dupilumab Fit Into Real-World Practice? Eric E. Low, Rena Yadlapati
57. Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling Moeez Rathore, Kimberly Curry, Wei Huang, Michel’le Wright, Daniel Martin, Jiyeon Baek, Derek Taylor, Masaru Miyagi, Wen Tang, Hao Feng, Yamu Li, Zhenghe Wang, Hallie Graor, Joseph Willis, Elizabeth Bryson, Christina S. Boutros, Omkar Desai, Bianca Islam, Lee M. Ellis, Stephen E. Moss, Jordan M. Winter, John Greenwood, Rui Wang
58. Immune Checkpoint Inhibitor–Induced Colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
59. Persistent Severe Abdominal Pain in a 40-Year-Old Male Patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
60. Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
61. Novel Immune Manipulators for IBD: Miniproteins! Eytan Wine
62. Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium, Maria Abreu, Paul Beck, Charles Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Anne Griffiths, David Guttman, Kevan Jacobson, Gilaad Kaplan, Denis O. Krause, Karen Madsen, John Marshall, Paul Moayyedi, Mark Ropeleski, Ernest Seidman, Mark Silverberg, Scott Snapper, Andy Stadnyk, A. Hillary Steinhart, Michael Surette, Dan Turner, Thomas Walters, Bruce Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee Denson, Colette Deslandres, Wael El-Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David Mack, Jerry McGrath, Anthony Otley, Remo Panancionne, Maria Abreu, Guy Aumais, Robert Baldassano, Charles Bernstein, Maria Cino, Lee Denson, Colette Deslandres, Wael El-Matary, Anne M. Griffiths, Charlotte Hedin, Hans Herfarth, Peter Higgins, Seamus Hussey, Hien Q. Huynh, Kevan Jacobson, David Keljo, David Kevans, Charlie Lees, David Mack, John Marshall, Jerry McGrath, Sanjay Murthy, Anthony Otley, Remo Panaccione, Nimisha Parekh, Sophie Plamondon, Graham Radford-Smith, Mark Ropeleski, Joel Rosh, David Rubin, Michael Schultz, Ernest Seidman, Corey Siegel, Scott Snapper, A. Hillary Steinhart, Dan Turner
63. The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
64. Use of Large Language Models to Identify Surveillance Colonoscopy Intervals—A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
65. Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nachef, Paul Feuerstadt, Thomas J. Borody, Sahil Khanna, Shrish Budree, Zain Kassam
66. Hidden Footprints in Ascites: Lessons From a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
67. Corrigendum
68. Surveillance for Hepatocellular Carcinoma in Cirrhosis: End of Monopoly for Serum Alpha Fetoprotein Lung-Yi Mak, Man-Fung Yuen
69. A Brain-Gut Pathway for Stress-Induced Microbiome Change Sarah A. Najjar, Kara Gross Margolis
70. Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler, Elena Sonnenberg, Michael Schumann, Lea-Maxie Haag, Dieter Beule, Lukas Flatz, TRR241 IBDome Consortium, Zlatko Trjanoski, Geert D’Haens, Carl Weidinger, Henrik E. Mei, Britta Siegmund, Kevin Thurley, Ahmed N. Hegazy
71. The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
72. It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About Inflammatory Bowel Disease Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
73. Reply Hanseul Kim, Long H. Nguyen
74. Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
75. Reply Fernando Azpiroz
76. Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
77. Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren
78. Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
79. Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
80. Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
81. Interventions for Improving Quality of Colonoscopy Qing-Hua Wang, Min Zhang, Hua Chen, Wei Han
82. Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
83. Focus on Psychological Intervention: Insights from Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention Chenhong Tian, Changlin Zhai, Haihua Pan
84. Detection of Gastrointestinal Bleeding With Large Language Models to Aid Quality Improvement and Appropriate Reimbursement Neil S. Zheng, Vipina K. Keloth, Kisung You, Daniel Kats, Darrick K. Li, Ohm Deshpande, Hamita Sachar, Hua Xu, Loren Laine, Dennis L. Shung
85. Obesity-Facilitated Colon Cancer Progression Is Mediated by Increased Diacylglycerol O-Acyltransferases 1 and 2 Levels Jenisha Ghimire, Morgan E. Collins, Patricia Snarski, Angelle N. King, Emmanuelle Ruiz, Rida Iftikhar, Harrison M. Penrose, Krzysztof Moroz, Tyler Rorison, Melody Baddoo, Muhammad Anas Naeem, Arnold H. Zea, Scott T. Magness, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
86. Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells Sarah A. Dooley, Elena Kolobova, Andreanna Burman, Izumi Kaji, Jessica R. Digrazia, Rachel Stubler, Anna Goldstein, Charulekha Packirisamy, Alexander W. Coutts, Milena Saqui-Salces, Nan Gao, Melinda A. Engevik, Mitchell D. Shub, James R. Goldenring, Amy C. Engevik
87. A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex Befeler, Stephanie Page-Lester, Nabihah Tayob, Sudhir Srivastava, Jo Ann Rinaudo, Amit G. Singal, K. Rajender Reddy, Jorge A. Marrero
88. Reply Timothy B. Gardner, Walter G. Park, Peter J. Allen
89. The Brain and the Immune System: A Dynamic Duo in Detecting and Defending Lin Y. Hung, Kara Gross Margolis
90. Comments on “Diagnosis and Management of Pancreatic Cysts” Santhi Swaroop Vege
91. Reevaluating Stemness in the Intestinal Crypt Samuel Asfaha, Nicola L. Jones
92. EUS-Guided Rendezvous Versus Needle-Knife Sphincterotomy After Difficult Biliary Cannulation in ERCP for Benign Disease Nauzer Forbes
93. Dual Targeting of Syndecan-1 and Glucose Transporter-1 With a Novel Lipid-Based Delivery System Enhances Therapeutic Efficacy and Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma Hari Krishna Rachamala, Naga Malleswara Rao Nakka, Ramcharan Singh Angom, Santanu Bhattacharya, Krishnendu Pal, Debabrata Mukhopadhyay
94. Stress Ulcer Prophylaxis in the Intensive Care Unit: More Evidence of Benefit Rishad Khan
95. Where do Noninvasive Colorectal Cancer Tools “FIT” Alongside Colonoscopy in the Surveillance of High-Risk Patients? Kevin J. Monahan
96. AGA Clinical Practice Update on Integrating Potassium-Competitive Acid Blockers Into Clinical Practice: Expert Review Amit Patel, Loren Laine, Paul Moayyedi, Justin Wu
97. A Head-to Head Comparison of Risankizumab and Ustekinumab as Second-Line Therapy in Moderate to Severely Active Crohn’s Disease Pavel S. Roshanov, Reena Khanna
98. Proteomic Biomarkers in Serum Predict Villous Atrophy Development in Asymptomatic Potential Celiac Disease Children at Time of Diagnosis Renata Auricchio, Roberta Mandile, Janneke Samsom, Chiara Esposito, Rossella de Cegli, Luigi Greco, European Laboratory for Food Induced Disease (ELFID) Group
99. Portal Fibrosis and the Ductular Reaction: Pathophysiological Role in the Progression of Liver Disease and Translational Opportunities Vikas Gupta, Tejasav S. Sehrawat, Massimo Pinzani, Mario Strazzabosco
100. Reply Ali Rezaie, Yee Hui Yeo
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近期历史最近 100 条记录

2024-11-13 Sucrase isomaltase dysfunction reduces sucrose intake in mice and humans Peter Aldiss, Leire Torices, Stina Ramne, Marit Eika Jørgensen, Sucrase-Isomaltase Working Group, Mauro D’Amato, Mette K. Andersen
2024-11-12 Exploring the Potential of Real-Time Audio-Visual Interactions of ChatGPT-4o in Endoscopy Training and Practice Qiqi Wu
2024-11-09 An Unexpected Cause of Fistulizing Small Intestinal Disease Saam Dilmaghani, Rondell P. Graham, Seth Sweetser
2024-11-08 CREEPING FAT-DERIVED FREE FATTY ACIDS INDUCE HYPERPLASIA OF INTESTINAL MUSCULARIS PROPRIA MUSCLE CELLS – A NOVEL LINK BETWEEN FAT AND INTESTINAL STRICTURE FORMATION IN CROHN’S DISEASE Weiwei Liu, Ren Mao, Thi Hong Nga Le, Gail West, Venkateshwari Varadharajan, Rakhee Banerjee, Genevieve Doyon, Pranab Mukherjee, Quang Tam Nguyen, Anny Mulya, Julie H. Rennison, Ilyssa O. Gordon, Michael Cruise, Shaomin Hu, Doug Czarnecki, Thomas Plesec,
2024-11-08 Phase 3 validation of PAaM for hepatocellular carcinoma risk stratification in cirrhosis Naoto Fujiwara, Camden Lopez, Tracey L. Marsh, Indu Raman, Cesia A. Marquez, Subhojit Paul, Sumit K. Mishra, Naoto Kubota, Courtney Katz, Hiroaki Kanzaki, Michael Gonzalez, Lisa Quirk, Sneha Deodhar, Pratibha Selvakumar, Prithvi Raj, Neehar D. Parikh, Lew
2024-11-07 Hacking Death in Dublin Seamus O'Mahony
2024-11-07 Corrigendum
2024-11-07 An intriguing case of hepatosplenic lesions and pneumonia during anti-TNF therapy for IBD. Gabriel Luiz de Almeida Souza, Vinicius Andrade Chebli, Julio Maria Fonseca Chebli
2024-11-07 A Rare Case of Enterocolitis with a Rare Cause Hirotaka Nakamura, Daisuke Watanabe, Yuzo Kodama
2024-11-07 Adverse Events Associated with Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-analysis Kirles Bishay, Zhao Wu Meng, Rishad Khan, Mehul Gupta, Yibing Ruan, Marcus Vaska, Jordan Iannuzzi, Dylan E. O’Sullivan, Brittany Mah, Arun C.R. Partridge, Amanda M. Henderson, Howard Guo, Sunil Samnani, Max DeMarco, Yuhong Yuan, B. Joseph Elmunzer, Rajesh
2024-11-05 The new horizon of Clostridioides difficile infection treatment Ed.J. Kuijper, Kevin W. Garey
2024-11-02 Comments on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Xian-hui Zhang, Yang Liu, Yu-xiang Gao, James Cheng-Chung Wei, Li-yun Zhang
2024-11-02 Esophagogastroduodenoscopy for Positive Fecal Immunochemical Test Screeners? Much Done, More to Be Considered. Lizhi Yi, Xiaoli Ren, Zhengyu Cheng
2024-11-02 FIT-positive individuals: is timely upper GI endoscopy necessary? Yunmeng Nie, Jianyu Lv, Junbin Yan
2024-11-01 Comment on “Risk of Cancers Proximal to the Colon in Fecal Immunochemical Test Positive Screenees in a Colorectal Cancer Screening Program” Jixuan Wu, Zili Zhang, Lei Zhang
2024-11-01 Reevaluating Confounders and Risk Interpretation in FIT-Positive Cancer Screening Jiashu Han, Dan Shan
2024-11-01 An Unusual Case of Gastric Multiple Lesions with Skin and Joint Abnormalities Haoran Jin, Feifan Chen, Jinlin Yang
2024-11-01 Reply to Nie et al, Zhang et al, Yi et al, Wu et al, and Han andShan Willemijn de Klaver, Manon van der Vlugt, Evelien Dekker
2024-10-29 The management of internal fistulizing Crohn’s disease in a child: more than meets the eye Kelsey Jones, Luba Plotkin, Stavros Loukogeorgakis, Ruth Cytter-Kuint, Austen Worth, Dan Turner
2024-10-29 A HIGH-RESOLUTION MICROENDOSCOPE IMPROVES ESOPHAGEAL CANCER SCREENING AND SURVEILLANCE: IMPLICATIONS FOR UNDERSERVED GLOBAL SETTINGS BASED ON AN INTERNATIONAL, RANDOMIZED CONTROLLED TRIAL Mimi C. Tan, Zhengqi Li, Kalpesh K. Patel, Fan Zhang, Xinying Yu, Xueshan Wang, Daniel G. Rosen, Sanford M. Dawsey, Liyan Xue, Chin Hur, Richard A. Schwarz, Imran Vohra, Yubo Tang, Mengfen Wu, Tao Wang, Jennifer Carns, Hong Xu, Rebecca R. Richards-Kortum,
2024-10-26 Differing Epithelial and Immunologic Activation Patterns Following Food Reintroduction Reveal Different Transcriptional Profiles in Active Eosinophilic Esophagitis Ashley L. Pyne, Amiko M. Uchida, Mark W. Hazel, Maria A. Pletneva, Kristina Allen-Brady, Kathryn A. Peterson
2024-10-26 Multi-cohort analysis reveals altered archaea in colorectal cancer fecal samples across populations Tianhui Li, Olabisi Oluwabukola Coker, Yang Sun, Shiyu Li, Chuanfa Liu, Yufeng Lin, Sunny H. Wong, Yinglei Miao, Joseph JY. Sung, Jun Yu
2024-10-25 Reply Ingo Steinbrück
2024-10-25 Evaluation of the Cold Versus Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps in the German CHRONICLE Trial Yu Yang, Yaling Li, Chengzi Huang, Ting Yu, Jun Li
2024-10-24 Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder Juan Pablo Arab, Alexandre Louvet, Maja Thiele, Gerald S. Winder, Robert J. Wong, Ashwani K. Singal
2024-10-23 Faecalibacterium prausnitzii Is Associated With Clinical Response to Immune Checkpoint Inhibitors in Patients With Advanced Gastric Adenocarcinoma: Results of Microbiota Analysis of PRODIGE 59-FFCD 1707-DURIGAST Trial Marius Bredon, Karine Le Malicot, Christophe Louvet, Ludovic Evesque, Daniel Gonzalez, David Tougeron, Harry Sokol
2024-10-23 Burn the Fat: Colon Cancer Tumors Are Skilled at Lipid Storage During Obesity Arianne L. Theiss, Christopher S. Williams
2024-10-23 Detailed Information on Cold Snare Resection in Large Colorectal Polyps Koki Nakajima, Hiroaki Saito, Yoshitaka Nishikawa
2024-10-23 Reply Tanawat Geeratragool, Uayporn Kaosombatwattana
2024-10-23 Assessing the Preventative Effects of Vonoprazan Relative to Intravenous Proton Pump Inhibitors Following Endoscopic Intervention in Peptic Ulcers Wei-Zheng Tang, Tai-Hang Liu, Ying-Bo Li
2024-10-22 CHRONICLE Trial: How Cool Is Cold Snaring for Endoscopic Mucosal Resection? Avinash Tiwari
2024-10-21 Enhancing Cold Snare Endoscopic Mucosal Resection: Addressing Efficacy Concerns and Margin Management Jia Xu, Xiaowei Tang
2024-10-19 Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis Ashwin N. Ananthakrishnan, M. Hassan Murad, Frank I. Scott, Manasi Agrawal, John P. Haydek, Berkeley N. Limketkai, Edward V. Loftus, Siddharth Singh
2024-10-18 Table of Contents
2024-10-18 Cover 1
2024-10-18 Editorial Board
2024-10-18 Elsewhere in The AGA Journals (Preview Section)
2024-10-18 Disparities in Gastrointestinal Health for US Immigrant Populations, and Strategies to Address These Disparities Miguel Malespin, Saikiran M. Kilaru
2024-10-18 CME Exam 1: Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies
2024-10-18 Prospective Analysis of Liver Stiffness Measurement by Vibration Controlled Transient Elastography as a Predictor of Outcomes in Biliary Atresia Jean P. Molleston, Nathan P. Goodrich, Wen Ye, Daniel H. Leung, Ronald J. Sokol, Benjamin L. Shneider, Children Force Outcomes Working Group
2024-10-18 Comments on “Association of GLP-1 Receptor Agonists and Hepatocellular Carcinoma Incidence and Hepatic Decompensation in Patients With Type 2 Diabetes” James Cheng-Chung Wei, Ching-Nung Wu, Wei-Chun Cheng
2024-10-18 Methodology of Study on Glucagon-like Peptide-1 Receptor Agonists and Hepatocellular Carcinoma Risk James Cheng-Chung Wei, Poi Kuo, Qi Mei
2024-10-18 Evolutionary Medicine for Chronic Inflammatory Diseases of the Gut: More Than a Clinical Fantasy? Nadia Andrea Andreani, Daniel Unterweger, Stefan Schreiber, John F. Baines
2024-10-18 Insights Into the Protective Role of GLP-1RAs in the Treatment of Type 2 Diabetes Mellitus: Implications for Hepatocellular Carcinoma and Hepatic Dysfunction Ziyi Wang, Jun Li, Yaling Li
2024-10-17 A “How-to” Guide For Establishing an Effective Trainee Mentorship Program Kirstie Lithgow, Jordan Iannuzzi, Kelle Hurd, Suqing Li
2024-10-17 GLP-1 Receptor Agonists' Role in Reducing Hepatocellular Carcinoma Risk Zaoqu Liu, Dan Shan, Xinwei Han
2024-10-17 In Memoriam: Ikuo Hirano, MD Nirmala Gonsalves, Steven Flamm, Gary W. Falk, David A. Katzka
2024-10-17 AGA Clinical Practice Update on Advances in Per-Oral Endoscopic Myotomy (POEM) and Remaining Questions—What We Have Learned in the Past Decade: Expert Review Dennis Yang, Robert Bechara, Christy M. Dunst, Vani J.A. Konda
2024-10-16 Reply Rong Xu
2024-10-16 Neurons on a Mission: Glial Global Positioning System for the Gut Reboot! Chalystha Yie Qin Lee, Kara Gross Margolis
2024-10-15 Placebo Rates in Crohn’s Disease Randomized Clinical Trials: An Individual Patient Data Meta-analysis Virginia Solitano, Malcolm Hogan, Siddharth Singh, Silvio Danese, Laurent Peyrin-Biroulet, Guangyong Zou, Yuhong Yuan, Bruce E. Sands, Brian G. Feagan, Parambir S. Dulai, Neeraj Narula, Christopher Ma, Vipul Jairath
2024-10-15 Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype) Malin Fromme, Audrey Payancé, Mattias Mandorfer, Katrine H. Thorhauge, Monica Pons, Marc Miravitlles, Jan Stolk, Bart van Hoek, Guido Stirnimann, Sona Frankova, Jan Sperl, Andreas E. Kremer, Barbara Burbaum, Christina Schrader, Amine Kadioglu, Michelle Wa
2024-10-14 Unveiling a Critical Role of IL-7 in Celiac Disease — Insights From a Novel Human Autoimmune Organoid Model Daniel Kotlarz
2024-10-14 Comparing the Performance of Commonly Used Fecal Immunochemical Tests Nauzer Forbes
2024-10-10 Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling Moeez Rathore, Kimberly Curry, Wei Huang, Michel’le Wright, Daniel Martin, Jiyeon Baek, Derek Taylor, Masaru Miyagi, Wen Tang, Hao Feng, Yamu Li, Zhenghe Wang, Hallie Graor, Joseph Willis, Elizabeth Bryson, Christina S. Boutros, Omkar Desai, Bianca Islam,
2024-10-09 Eosinophils Are Just the Tip of the Iceberg for Eosinophilic Esophagitis Eric E. Low, Rena Yadlapati
2024-10-09 The First Approved Therapy in Infants and Young Children With EoE — Now the Big Question: Where Will Dupilumab Fit Into Real-World Practice? Eric E. Low, Rena Yadlapati
2024-10-09 Persistent Severe Abdominal Pain in a 40-Year-Old Male Patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
2024-10-09 Novel Immune Manipulators for IBD: Miniproteins! Eytan Wine
2024-10-09 Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
2024-10-08 Immune Checkpoint Inhibitor–Induced Colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
2024-10-08 Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium, Maria Abreu, Paul Beck, Charles Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Ann
2024-10-03 The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
2024-10-02 Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nac
2024-10-02 Use of Large Language Models to Identify Surveillance Colonoscopy Intervals—A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
2024-10-01 Hidden Footprints in Ascites: Lessons From a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
2024-10-01 Corrigendum
2024-09-28 Surveillance for Hepatocellular Carcinoma in Cirrhosis: End of Monopoly for Serum Alpha Fetoprotein Lung-Yi Mak, Man-Fung Yuen
2024-09-28 A Brain-Gut Pathway for Stress-Induced Microbiome Change Sarah A. Najjar, Kara Gross Margolis
2024-09-28 Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Li
2024-09-26 It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About Inflammatory Bowel Disease Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
2024-09-26 The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
2024-09-21 Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
2024-09-21 Reply Fernando Azpiroz
2024-09-21 Reply Hanseul Kim, Long H. Nguyen
2024-09-21 Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
2024-09-20 Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
2024-09-20 Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
2024-09-20 Interventions for Improving Quality of Colonoscopy Qing-Hua Wang, Min Zhang, Hua Chen, Wei Han
2024-09-20 Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
2024-09-20 Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
2024-09-20 Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren
2024-09-20 Focus on Psychological Intervention: Insights from Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention Chenhong Tian, Changlin Zhai, Haihua Pan
2024-09-19 Editorial Board
2024-09-19 Table of Contents
2024-09-19 Cover 1
2024-09-19 Interventions to Increase Follow-Up of Abnormal Stool-Based Colorectal Cancer Screening Tests in Safety Net Settings: A Systematic Review Rachel B. Issaka, Ari Bell-Brown, Teresa Jewell, Sara L. Jackson, Bryan J. Weiner
2024-09-19 CME Exam 2: Prognostic Factors for Early Recurrence After Resection of Pancreatic Cancer: A Systematic Review and Meta-Analysis
2024-09-19 Elsewhere in The AGA Journals (Preview Section)
2024-09-19 CME Exam 1: Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis
2024-09-18 Detection of Gastrointestinal Bleeding With Large Language Models to Aid Quality Improvement and Appropriate Reimbursement Neil S. Zheng, Vipina K. Keloth, Kisung You, Daniel Kats, Darrick K. Li, Ohm Deshpande, Hamita Sachar, Hua Xu, Loren Laine, Dennis L. Shung
2024-09-18 Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells Sarah A. Dooley, Elena Kolobova, Andreanna Burman, Izumi Kaji, Jessica R. Digrazia, Rachel Stubler, Anna Goldstein, Charulekha Packirisamy, Alexander W. Coutts, Milena Saqui-Salces, Nan Gao, Melinda A. Engevik, Mitchell D. Shub, James R. Goldenring, Amy C
2024-09-18 Obesity-Facilitated Colon Cancer Progression Is Mediated by Increased Diacylglycerol O-Acyltransferases 1 and 2 Levels Jenisha Ghimire, Morgan E. Collins, Patricia Snarski, Angelle N. King, Emmanuelle Ruiz, Rida Iftikhar, Harrison M. Penrose, Krzysztof Moroz, Tyler Rorison, Melody Baddoo, Muhammad Anas Naeem, Arnold H. Zea, Scott T. Magness, Erik F. Flemington, Susan E. C
2024-09-16 A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex Befeler, Stephanie Page-Lester, Nabihah Tayob, Sudhir Srivastava, Jo Ann Rinaudo, Amit G. Singal, K. Rajender Reddy, Jorge A. Marrero
2024-09-15 The Brain and the Immune System: A Dynamic Duo in Detecting and Defending Lin Y. Hung, Kara Gross Margolis
2024-09-15 Comments on “Diagnosis and Management of Pancreatic Cysts” Santhi Swaroop Vege
2024-09-15 Reply Timothy B. Gardner, Walter G. Park, Peter J. Allen
2024-09-14 Dual Targeting of Syndecan-1 and Glucose Transporter-1 With a Novel Lipid-Based Delivery System Enhances Therapeutic Efficacy and Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma Hari Krishna Rachamala, Naga Malleswara Rao Nakka, Ramcharan Singh Angom, Santanu Bhattacharya, Krishnendu Pal, Debabrata Mukhopadhyay
2024-09-14 Reevaluating Stemness in the Intestinal Crypt Samuel Asfaha, Nicola L. Jones
2024-09-14 Stress Ulcer Prophylaxis in the Intensive Care Unit: More Evidence of Benefit Rishad Khan

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