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| 1. | Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome | Ana Barettino, Cristina González-Gómez, Pilar Gonzalo, María J. Andrés-Manzano, Carlos R. Guerrero, Francisco M. Espinosa, Rosa M. Carmona, Yaazan Blanco, Beatriz Dorado, Carlos Torroja, Fátima Sánchez-Cabo, Ana Quintas, Alberto Benguría, Ana Dopazo, Ricardo García, Ignacio Benedicto, Vicente Andrés | |
| 2. | Rg3-lipo biomimetic delivery of paclitaxel enhances targeting of tumors and myeloid-derived suppressor cells | Yuru Shen, Bin Zhong, Wanwei Zheng, Dan Wang, Lin Chen, Huan Song, Xuanxuan Pan, Shaocong Mo, Bryan Jin, Haoshu Cui, Huaxing Zhan, Feifei Luo, Jie Liu | |
| 3. | Xylazine induces dopamine release and augments the effects of fentanyl | Joseph R. Trinko, Ethan Foscue, Edward M. Kong, Aakash Basu, Anouk M. Corstens, Summer L. Thompson, Alfred P. Kaye, Jane R. Taylor, Ralph J. DiLeone | |
| 4. | MGA loss-of-function variants cause premature ovarian insufficiency | Shuyan Tang, Ting Guo, Chengcheng Song, Lingbo Wang, Jun Zhang, Aleksandar Rajkovic, Xiaoqi Lin, Shiling Chen, Yujun Liu, Weidong Tian, Bangguo Wu, Shixuan Wang, Wenwen Wang, Yunhui Lai, Ao Wang, Shuhua Xu, Li Jin, Hanni Ke, Shidou Zhao, Yan Li, Yingying Qin, Feng Zhang, Zi-Jiang Chen | |
| 5. | 2024 Association of American Physicians Presidential AddressTransparency, bias, and reproducibility across science: a meta-research view | John P.A. Ioannidis | |
| 6. | 2024 American Physician Scientists Association Presidential AddressIt takes a village | Alex D. Waldman | |
| 7. | 2024 American Society for Clinical Investigation Presidential AddressSuper chickens, givers, and collective intelligence: the importance of collaboration, teamwork, and mentorship in science | Benjamin D. Humphreys | |
| 8. | 2024 Association of American Physicians George M. Kober LectureGenetics of hemostasis: from bedside to bench and back again | David Ginsburg | |
| 9. | Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles | Maryam Rezaei, Manqi Liang, Zeynep Yalcin, Jacinta H. Martin, Parinaz Kazemi, Eric Bareke, Zhao-Jia Ge, Majid Fardaei, Claudio Benadiva, Reda Hemida, Adnan Hassan, Geoffrey J. Maher, Ebtesam Abdalla, William Buckett, Pierre-Adrien Bolze, Iqbaljit Sandhu, Onur Duman, Suraksha Agrawal, JianHua Qian, Jalal Vallian Broojeni, Lavi Bhati, Pierre Miron, Fabienne Allias, Amal Selim, Rosemary A. Fisher, Michael J. Seckl, Philippe Sauthier, Isabelle Touitou, Seang Lin Tan, Jacek Majewski, Teruko Taketo, Rima Slim | |
| 10. | Parkin activates innate immunity and promotes antitumor immune responses | Michela Perego, Minjeong Yeon, Ekta Agarwal, Andrew T. Milcarek, Irene Bertolini, Chiara Camisaschi, Jagadish C. Ghosh, Hsin-Yao Tang, Nathalie Grandvaux, Marcus Ruscetti, Andrew V. Kossenkov, Sarah Preston-Alp, Italo Tempera, Noam Auslander, Dario C. Altieri | |
| 11. | Parkin paves the path to antitumor immunity: Expanding Parkin’s role as a tumor suppressor | Hyungsoo Kim, Ze’ev A. Ronai | |
| 12. | Neuropilin-2–expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling | Ayush Kumar, Hira Lal Goel, Christi A. Wisniewski, Tao Wang, Yansong Geng, Mengdie Wang, Shivam Goel, Kai Hu, Rui Li, Lihua J. Zhu, Jennifer L. Clark, Lindsay M. Ferreira, Michael A. Brehm, Thomas J. FitzGerald, Arthur M. Mercurio | |
| 13. | Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation | Shuai Wang, Tengfei Huang, Qiulian Wu, Huairui Yuan, Xujia Wu, Fanen Yuan, Tingting Duan, Suchet Taori, Yingming Zhao, Nathaniel W. Snyder, Dimitris G. Placantonakis, Jeremy N. Rich | |
| 14. | Stimulation of an entorhinal-hippocampal extinction circuit facilitates fear extinction in a post-traumatic stress disorder model | Ze-Jie Lin, Xue Gu, Wan-Kun Gong, Mo Wang, Yan-Jiao Wu, Qi Wang, Xin-Rong Wu, Xin-Yu Zhao, Michael X. Zhu, Lu-Yang Wang, Quanying Liu, Ti-Fei Yuan, Wei-Guang Li, Tian-Le Xu | |
| 15. | Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1 | Yong Liu, Zhi Yang, Shuanglian Wang, Rui Miao, Chiung-Wen Mary Chang, Jingyu Zhang, Xin Zhang, Mien-Chie Hung, Junwei Hou | |
| 16. | Cell-cycle machinery is critical in regulating uterine steroid hormone for embryo implantation and development | Francesco J. DeMayo | |
| 17. | Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis | Xianpeng Liu, Ziyou Ren, Can Tan, Félix L. Núñez-Santana, Megan E. Kelly, Yuanqing Yan, Haiying Sun, Hiam Abdala-Valencia, Wenbin Yang, Qiang Wu, Takahide Toyoda, Marija Milisav, S. Marina Casalino-Matsuda, Emilia Lecuona, Emily Jeong Cerier, Lena J. Heung, Mohamed E. Abazeed, Harris Perlman, Ruli Gao, Navdeep S. Chandel, G.R. Scott Budinger, Ankit Bharat | |
| 18. | Uterine cyclin A2–deficient mice as a model of female early pregnancy loss | Fatimah Aljubran, Katelyn Schumacher, Amanda Graham, Sumedha Gunewardena, Courtney Marsh, Michael Lydic, Kristin Holoch, Warren B. Nothnick | |
| 19. | Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function | Hanae Lahlou, Hong Zhu, Wu Zhou, Albert S.B. Edge | |
| 20. | TSC/mTORC1 mediates mTORC2/AKT1 signaling in c-MYC–induced murine hepatocarcinogenesis via centromere protein M | Yi Zhou, Shu Zhang, Guoteng Qiu, Xue Wang, Andrew Yonemura, Hongwei Xu, Guofei Cui, Shanshan Deng, Joanne Chun, Nianyong Chen, Meng Xu, Xinhua Song, Jingwen Wang, Zijing Xu, Youping Deng, Matthias Evert, Diego F. Calvisi, Shumei Lin, Haichuan Wang, Xin Chen | |
| 21. | Dual targeting macrophages and microglia is a therapeutic vulnerability in models of PTEN-deficient glioblastoma | Yang Liu, Junyan Wu, Hinda Najem, Yiyun Lin, Lizhi Pang, Fatima Khan, Fei Zhou, Heba Ali, Amy B. Heimberger, Peiwen Chen | |
| 22. | CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia | Paul Deschamps, Margaux Wacheux, Axel Gosseye, Margot Morabito, Arnaud Pagès, Anne-Marie Lyne, Alexia Alfaro, Philippe Rameau, Aygun Imanci, Rabie Chelbi, Valentine Marchand, Aline Renneville, Mrinal M. Patnaik, Valerie Lapierre, Bouchra Badaoui, Orianne Wagner-Ballon, Céline Berthon, Thorsten Braun, Christophe Willekens, Raphael Itzykson, Pierre Fenaux, Sylvain Thépot, Gabriel Etienne, Emilie Elvira-Matelot, Francoise Porteu, Nathalie Droin, Leïla Perié, Lucie Laplane, Eric Solary, Dorothée Selimoglu-Buet | |
| 23. | Long-lived lung megakaryocytes contribute to platelet recovery in thrombocytopenia models | Alison C. Livada, Kathleen E. McGrath, Michael W. Malloy, Chen Li, Sara K. Ture, Paul D. Kingsley, Anne D. Koniski, Leah A. Vit, Katherine E. Nolan, Deanne Mickelsen, Grace E. Monette, Preeti Maurya, James Palis, Craig N. Morrell | |
| 24. | Innate immune cell activation by adjuvant AS01 in human lymph node explants is age independent | Vicki V. Stylianou, Kirstie M. Bertram, Van Anh Vo, Elizabeth B. Dunn, Heeva Baharlou, Darcii J. Terre, James Elhindi, Elisabeth Elder, James French, Farid Meybodi, Stéphane T. Temmerman, Arnaud M. Didierlaurent, Margherita Coccia, Kerrie J. Sandgren, Anthony L. Cunningham | |
| 25. | Insulin-like growth factor 2 drives fibroblast-mediated tumor immunoevasion and confers resistance to immunotherapy | Daqiang Song, Yushen Wu, Jie Li, Jiazhou Liu, Ziying Yi, Xiaoyu Wang, Jiazheng Sun, Liuying Li, Qianxue Wu, Yuru Chen, Huiying Fang, Tiankuo Luan, Huimin Du, Jing Huang, Weiyan Peng, Yuxian Wei, Fan Li, Qin Li, Li Zhang, Yong Zhu, Jingyuan Wan, Guosheng Ren, Hongzhong Li | |
| 26. | The lung is a megakaryocyte outpost that can defend against thrombocytopenic attack | Anthony K. Yeung, George J. Murphy | |
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近期历史最近 100 条记录
| 2024-11-16 | Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome | Ana Barettino, Cristina González-Gómez, Pilar Gonzalo, María J. Andrés-Manzano, Carlos R. Guerrero, Francisco M. Espinosa, Rosa M. Carmona, Yaazan Blanco, Beatriz Dorado, Carlos Torroja, Fátima Sánchez-Cabo, Ana Quintas, Alberto Benguría, Ana Dopazo, Rica | |
| 2024-11-16 | Rg3-lipo biomimetic delivery of paclitaxel enhances targeting of tumors and myeloid-derived suppressor cells | Yuru Shen, Bin Zhong, Wanwei Zheng, Dan Wang, Lin Chen, Huan Song, Xuanxuan Pan, Shaocong Mo, Bryan Jin, Haoshu Cui, Huaxing Zhan, Feifei Luo, Jie Liu | |
| 2024-11-16 | Xylazine induces dopamine release and augments the effects of fentanyl | Joseph R. Trinko, Ethan Foscue, Edward M. Kong, Aakash Basu, Anouk M. Corstens, Summer L. Thompson, Alfred P. Kaye, Jane R. Taylor, Ralph J. DiLeone | |
| 2024-11-16 | MGA loss-of-function variants cause premature ovarian insufficiency | Shuyan Tang, Ting Guo, Chengcheng Song, Lingbo Wang, Jun Zhang, Aleksandar Rajkovic, Xiaoqi Lin, Shiling Chen, Yujun Liu, Weidong Tian, Bangguo Wu, Shixuan Wang, Wenwen Wang, Yunhui Lai, Ao Wang, Shuhua Xu, Li Jin, Hanni Ke, Shidou Zhao, Yan Li, Yingying | |
| 2024-11-16 | 2024 Association of American Physicians Presidential AddressTransparency, bias, and reproducibility across science: a meta-research view | John P.A. Ioannidis | |
| 2024-11-16 | 2024 American Physician Scientists Association Presidential AddressIt takes a village | Alex D. Waldman | |
| 2024-11-16 | 2024 American Society for Clinical Investigation Presidential AddressSuper chickens, givers, and collective intelligence: the importance of collaboration, teamwork, and mentorship in science | Benjamin D. Humphreys | |
| 2024-11-16 | 2024 Association of American Physicians George M. Kober LectureGenetics of hemostasis: from bedside to bench and back again | David Ginsburg | |
| 2024-11-16 | Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles | Maryam Rezaei, Manqi Liang, Zeynep Yalcin, Jacinta H. Martin, Parinaz Kazemi, Eric Bareke, Zhao-Jia Ge, Majid Fardaei, Claudio Benadiva, Reda Hemida, Adnan Hassan, Geoffrey J. Maher, Ebtesam Abdalla, William Buckett, Pierre-Adrien Bolze, Iqbaljit Sandhu, | |
| 2024-11-16 | Parkin activates innate immunity and promotes antitumor immune responses | Michela Perego, Minjeong Yeon, Ekta Agarwal, Andrew T. Milcarek, Irene Bertolini, Chiara Camisaschi, Jagadish C. Ghosh, Hsin-Yao Tang, Nathalie Grandvaux, Marcus Ruscetti, Andrew V. Kossenkov, Sarah Preston-Alp, Italo Tempera, Noam Auslander, Dario C. Alt | |
| 2024-11-16 | Parkin paves the path to antitumor immunity: Expanding Parkin’s role as a tumor suppressor | Hyungsoo Kim, Ze’ev A. Ronai | |
| 2024-11-16 | Neuropilin-2–expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling | Ayush Kumar, Hira Lal Goel, Christi A. Wisniewski, Tao Wang, Yansong Geng, Mengdie Wang, Shivam Goel, Kai Hu, Rui Li, Lihua J. Zhu, Jennifer L. Clark, Lindsay M. Ferreira, Michael A. Brehm, Thomas J. FitzGerald, Arthur M. Mercurio | |
| 2024-11-16 | Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation | Shuai Wang, Tengfei Huang, Qiulian Wu, Huairui Yuan, Xujia Wu, Fanen Yuan, Tingting Duan, Suchet Taori, Yingming Zhao, Nathaniel W. Snyder, Dimitris G. Placantonakis, Jeremy N. Rich | |
| 2024-11-16 | Stimulation of an entorhinal-hippocampal extinction circuit facilitates fear extinction in a post-traumatic stress disorder model | Ze-Jie Lin, Xue Gu, Wan-Kun Gong, Mo Wang, Yan-Jiao Wu, Qi Wang, Xin-Rong Wu, Xin-Yu Zhao, Michael X. Zhu, Lu-Yang Wang, Quanying Liu, Ti-Fei Yuan, Wei-Guang Li, Tian-Le Xu | |
| 2024-11-16 | Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1 | Yong Liu, Zhi Yang, Shuanglian Wang, Rui Miao, Chiung-Wen Mary Chang, Jingyu Zhang, Xin Zhang, Mien-Chie Hung, Junwei Hou | |
| 2024-11-16 | Cell-cycle machinery is critical in regulating uterine steroid hormone for embryo implantation and development | Francesco J. DeMayo | |
| 2024-11-16 | Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis | Xianpeng Liu, Ziyou Ren, Can Tan, Félix L. Núñez-Santana, Megan E. Kelly, Yuanqing Yan, Haiying Sun, Hiam Abdala-Valencia, Wenbin Yang, Qiang Wu, Takahide Toyoda, Marija Milisav, S. Marina Casalino-Matsuda, Emilia Lecuona, Emily Jeong Cerier, Lena J. Heun | |
| 2024-11-16 | Uterine cyclin A2–deficient mice as a model of female early pregnancy loss | Fatimah Aljubran, Katelyn Schumacher, Amanda Graham, Sumedha Gunewardena, Courtney Marsh, Michael Lydic, Kristin Holoch, Warren B. Nothnick | |
| 2024-11-16 | Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function | Hanae Lahlou, Hong Zhu, Wu Zhou, Albert S.B. Edge | |
| 2024-11-16 | TSC/mTORC1 mediates mTORC2/AKT1 signaling in c-MYC–induced murine hepatocarcinogenesis via centromere protein M | Yi Zhou, Shu Zhang, Guoteng Qiu, Xue Wang, Andrew Yonemura, Hongwei Xu, Guofei Cui, Shanshan Deng, Joanne Chun, Nianyong Chen, Meng Xu, Xinhua Song, Jingwen Wang, Zijing Xu, Youping Deng, Matthias Evert, Diego F. Calvisi, Shumei Lin, Haichuan Wang, Xin Ch | |
| 2024-11-16 | Dual targeting macrophages and microglia is a therapeutic vulnerability in models of PTEN-deficient glioblastoma | Yang Liu, Junyan Wu, Hinda Najem, Yiyun Lin, Lizhi Pang, Fatima Khan, Fei Zhou, Heba Ali, Amy B. Heimberger, Peiwen Chen | |
| 2024-11-16 | CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia | Paul Deschamps, Margaux Wacheux, Axel Gosseye, Margot Morabito, Arnaud Pagès, Anne-Marie Lyne, Alexia Alfaro, Philippe Rameau, Aygun Imanci, Rabie Chelbi, Valentine Marchand, Aline Renneville, Mrinal M. Patnaik, Valerie Lapierre, Bouchra Badaoui, Orianne | |
| 2024-11-16 | Long-lived lung megakaryocytes contribute to platelet recovery in thrombocytopenia models | Alison C. Livada, Kathleen E. McGrath, Michael W. Malloy, Chen Li, Sara K. Ture, Paul D. Kingsley, Anne D. Koniski, Leah A. Vit, Katherine E. Nolan, Deanne Mickelsen, Grace E. Monette, Preeti Maurya, James Palis, Craig N. Morrell | |
| 2024-11-16 | Innate immune cell activation by adjuvant AS01 in human lymph node explants is age independent | Vicki V. Stylianou, Kirstie M. Bertram, Van Anh Vo, Elizabeth B. Dunn, Heeva Baharlou, Darcii J. Terre, James Elhindi, Elisabeth Elder, James French, Farid Meybodi, Stéphane T. Temmerman, Arnaud M. Didierlaurent, Margherita Coccia, Kerrie J. Sandgren, Ant | |
| 2024-11-16 | Insulin-like growth factor 2 drives fibroblast-mediated tumor immunoevasion and confers resistance to immunotherapy | Daqiang Song, Yushen Wu, Jie Li, Jiazhou Liu, Ziying Yi, Xiaoyu Wang, Jiazheng Sun, Liuying Li, Qianxue Wu, Yuru Chen, Huiying Fang, Tiankuo Luan, Huimin Du, Jing Huang, Weiyan Peng, Yuxian Wei, Fan Li, Qin Li, Li Zhang, Yong Zhu, Jingyuan Wan, Guosheng R | |
| 2024-11-16 | The lung is a megakaryocyte outpost that can defend against thrombocytopenic attack | Anthony K. Yeung, George J. Murphy | |
| 2024-11-02 | The importance of diverse multiomics datasets and analyses | Laura J. Rasmussen-Torvik | |
| 2024-11-02 | Activation of STAT3-mediated ciliated cell survival protects against severe infection by respiratory syncytial virus | Caiqi Zhao, Yan Bai, Wei Wang, Gaurang M. Amonkar, Hongmei Mou, Judith Olejnik, Adam J. Hume, Elke Mühlberger, Nicholas W. Lukacs, Rachel Fearns, Paul H. Lerou, Xingbin Ai | |
| 2024-11-02 | Enhanced susceptibility of pediatric airway epithelium to respiratory syncytial virus infection | Raymond J. Pickles, Gang Chen, Scott H. Randell | |
| 2024-11-02 | Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans | Usman A. Tahir, Jacob L. Barber, Daniel E. Cruz, Meltem Ece Kars, Shuliang Deng, Bjoernar Tuftin, Madeline G. Gillman, Mark D. Benson, Jeremy M. Robbins, Zsu-Zsu Chen, Prashant Rao, Daniel H. Katz, Laurie Farrell, Tamar Sofer, Michael E. Hall, Lynette Eku | |
| 2024-11-02 | Hidradenitis suppurativa: key insights into treatment success and failure | Kelsey R. van Straalen, Vincent Piguet, Johann E. Gudjonsson | |
| 2024-11-02 | The convergence of genomic medicine and translational omics in transforming breast cancer patient care | Sulin Wu, Yonglan Zheng, Olufunmilayo I. Olopade | |
| 2024-11-02 | Accumulation of Epstein-Barr virus–induced cross-reactive immune responses is associated with multiple sclerosis | Hannes Vietzen, Laura M. Kühner, Sarah M. Berger, Philippe L. Furlano, Gabriel Bsteh, Thomas Berger, Paulus Rommer, Elisabeth Puchhammer-Stöckl | |
| 2024-11-02 | Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma | Divya Nagarajan, Rebeca T. Parracho, David Corujo, Minglu Xie, Ginte Kutkaite, Thale K. Olsen, Marta Rubies Bedos, Maede Salehi, Ninib Baryawno, Michael P. Menden, Xingqi Chen, Marcus Buschbeck, Yumeng Mao | |
| 2024-11-02 | Antibiotic use during influenza infection augments lung eosinophils that impair immunity against secondary bacterial pneumonia | Marilia Sanches Santos Rizzo Zuttion, Tanyalak Parimon, Stephanie A. Bora, Changfu Yao, Katherine Lagree, Catherine A. Gao, Richard G. Wunderink, Georgios D. Kitsios, Alison Morris, Yingze Zhang, Bryan J. McVerry, Matthew E. Modes, Alberto M. Marchevsky, | |
| 2024-11-02 | TET3-overexpressing macrophages promote endometriosis | Haining Lv, Beibei Liu, Yangyang Dai, Feng Li, Stefania Bellone, Yuping Zhou, Ramanaiah Mamillapalli, Dejian Zhao, Muthukumaran Venkatachalapathy, Yali Hu, Gordon G. Carmichael, Da Li, Hugh S. Taylor, Yingqun Huang | |
| 2024-11-02 | A six-year study in a real-world population reveals an increased incidence of dyslipidemia during COVID-19 | Valentina Trimarco, Raffaele Izzo, Stanislovas S. Jankauskas, Mario Fordellone, Giuseppe Signoriello, Maria Virginia Manzi, Maria Lembo, Paola Gallo, Giovanni Esposito, Roberto Piccinocchi, Francesco Rozza, Carmine Morisco, Pasquale Mone, Gaetano Piccinoc | |
| 2024-11-02 | Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis | Federico Fondelli, Jana Willemyns, Roger Domenech-Garcia, Maria José Mansilla, Gerard Godoy-Tena, Anna G. Ferreté-Bonastre, Alex Agúndez-Moreno, Silvia Presas-Rodriguez, Cristina Ramo-Tello, Esteban Ballestar, Eva Martínez-Cáceres | |
| 2024-11-02 | Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity | Gianmarco Pallavicini, Amanda Moccia, Giorgia Iegiani, Roberta Parolisi, Emily R. Peirent, Gaia Elena Berto, Martina Lorenzati, Rami Y. Tshuva, Alessia Ferraro, Fiorella Balzac, Emilia Turco, Shachi U. Salvi, Hedvig F. Myklebust, Sophia Wang, Julia Eisenb | |
| 2024-11-02 | Targeting TET3 in macrophages provides a concept strategy for the treatment of endometriosis | Hossein Hosseinirad, Md Saidur Rahman, Jae-Wook Jeong | |
| 2024-11-02 | IL-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption | Guillermo S. Romano Ibarra, Lei Lei, Wenjie Yu, Andrew L. Thurman, Nicholas D. Gansemer, David K. Meyerholz, Alejandro A. Pezzulo, Paul B. McCray, Ian M. Thornell, David A. Stoltz | |
| 2024-11-02 | Experimental West Nile virus infection provides lessons for recovery from enteric neuropathies | Joel C. Bornstein | |
| 2024-11-02 | More T cell receptors to the RAScue in cancer? | Eric Tran | |
| 2024-11-02 | West Nile virus triggers intestinal dysmotility via T cell–mediated enteric nervous system injury | Hana Janova, Fang R. Zhao, Pritesh Desai, Matthias Mack, Larissa B. Thackray, Thaddeus S. Stappenbeck, Michael S. Diamond | |
| 2024-11-02 | Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors | Adham S. Bear, Rebecca B. Nadler, Mark H. O’Hara, Kelsey L. Stanton, Chong Xu, Robert J. Saporito, Andrew J. Rech, Miren L. Baroja, Tatiana Blanchard, Maxwell H. Elliott, Michael J. Ford, Richard Jones, Shivang Patel, Andrea Brennan, Zachary O’Neil, Danie | |
| 2024-11-02 | Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia | Rafael Ferraz-Bannitz, Berkcan Ozturk, Cameron Cummings, Vissarion Efthymiou, Pilar Casanova Querol, Lindsay Poulos, Hanna Wang, Valerie Navarrete, Hamayle Saeed, Christopher M. Mulla, Hui Pan, Jonathan M. Dreyfuss, Donald C. Simonson, Darleen A. Sandoval | |
| 2024-11-02 | CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA | Honghe Liu, Xiao-Feng Zhao, Yu-Ning Lu, Lindsey R. Hayes, Jiou Wang | |
| 2024-11-02 | Egfl6 promotes ovarian cancer progression by enhancing the immunosuppressive functions of tumor-associated myeloid cells | Sarah Hamze Sinno, Joshua A. Imperatore, Shoumei Bai, Noémie Gomes-Jourdan, Nyasha Mafarachisi, Claudia Coronnello, Linan Zhang, Eldin Jašarević, Hatice U. Osmanbeyoglu, Ronald J. Buckanovich, Sandra Cascio | |
| 2024-11-02 | PAC1 constrains type 2 inflammation through promotion of CGRP signaling in ILC2s | Yuan Jin, Bowen Liu, Qiuyu Li, Xiangyan Meng, Xiaowei Tang, Yan Jin, Yuxin Yin | |
| 2024-11-02 | RNASEH2B loss and PARP inhibition in advanced prostate cancer | Juliet Carmichael, Ines Figueiredo, Bora Gurel, Nick Beije, Wei Yuan, Jan Rekowski, George Seed, Suzanne Carreira, Claudia Bertan, Maria de Los Dolores Fenor de La Maza, Khobe Chandran, Antje Neeb, Jon Welti, Lewis Gallagher, Denisa Bogdan, Mateus Crespo, | |
| 2024-10-16 | Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture | Andreas Patsalos, Laszlo Halasz, Darby Oleksak, Xiaoyan Wei, Gergely Nagy, Petros Tzerpos, Thomas Conrad, David W. Hammers, H. Lee Sweeney, Laszlo Nagy | |
| 2024-10-16 | Discrimination of primary and chronic cytomegalovirus infection based on humoral immune profiles in pregnancy | Andrew P. Hederman, Christopher A.L. Remmel, Shilpee Sharma, Harini Natarajan, Joshua A. Weiner, Daniel Wrapp, Catherine Donner, Marie-Luce Delforge, Piera d’Angelo, Milena Furione, Chiara Fornara, Jason S. McLellan, Daniele Lilleri, Arnaud Marchant, Marg | |
| 2024-10-16 | Deciphering bone marrow engraftment after allogeneic stem cell transplantation in humans using single-cell analyses | Jennifer Bordenave, Dorota Gajda, David Michonneau, Nicolas Vallet, Mathieu Chevalier, Emmanuelle Clappier, Pierre Lemaire, Stéphanie Mathis, Marie Robin, Aliénor Xhaard, Flore Sicre de Fontbrune, Aurélien Corneau, Sophie Caillat-Zucman, Regis Peffault de | |
| 2024-10-16 | Timing of antiretroviral therapy initiation affects intact HIV reservoirs following analytical treatment interruption | Maegan R. Manning, Jana Blazkova, Jesse S. Justement, Victoria Shi, Brooke D. Kennedy, M. Ali Rai, Catherine A. Seamon, Kathleen Gittens, Michael C. Sneller, Susan Moir, Tae-Wook Chun | |
| 2024-10-16 | Conversations with JCI editors in chief | Ushma S. Neill | |
| 2024-10-16 | Elexacaftor/tezacaftor/ivacaftor’s effects on cystic fibrosis infections are maintained, but not increased, after 3.5 years of treatment | Sarah J. Morgan, Ellis Coulter, Hannah L. Betts, George M. Solomon, John P. Clancy, Steven M. Rowe, David P. Nichols, Pradeep K. Singh, the PROMISE-Micro Study Group | |
| 2024-10-16 | Retinal perivascular macrophages regulate immune cell infiltration during neuroinflammation in mouse models of ocular disease | Jacob K. Sterling, Amrita Rajesh, Steven Droho, Joyce Gong, Andrew L. Wang, Andrew P. Voigt, C. Elysse Brookins, Jeremy A. Lavine | |
| 2024-10-16 | Proton-activated chloride channel increases endplate porosity and pain in a mouse spine degeneration model | Peng Xue, Weixin Zhang, Mengxi Shen, Junhua Yang, Jiachen Chu, Shenyu Wang, Mei Wan, Junying Zheng, Zhaozhu Qiu, Xu Cao | |
| 2024-10-16 | Deficiency of parkin causes neurodegeneration and accumulation of pathological α-synuclein in monkey models | Rui Han, Qi Wang, Xin Xiong, Xiusheng Chen, Zhuchi Tu, Bang Li, Fei Zhang, Chunyu Chen, Mingtian Pan, Ting Xu, Laiqiang Chen, Zhifu Wang, Yanting Liu, Dajian He, Xiangyu Guo, Feng He, Peng Wu, Peng Yin, Yunbo Liu, Xiaoxin Yan, Shihua Li, Xiao-Jiang Li, We | |
| 2024-10-16 | Calcineurin inhibitor blocks tolerance by suppressing donor T cell terminal exhaustion after allogeneic hematopoietic cell transplantation | Hajime Senjo, Daigo Hashimoto, Takanori Teshima | |
| 2024-10-16 | Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply. | Ping Zhang, Simone A. Minnie, Geoffrey R. Hill | |
| 2024-10-16 | Neutralizing activity of anti–SARS-CoV-2 hyperimmune immunoglobulins and intravenous immunoglobulins against currently circulating SARS-CoV-2 variants | Lorenza Bellusci, Hana Golding, Surender Khurana | |
| 2024-10-16 | HOPE springs eternal: lack of HIV superinfection in HIV Organ Policy Equity Act kidney transplants | Christine M. Durand, Andrew D. Redd | |
| 2024-10-16 | Longitudinal analysis of viral dynamics in HIV+-to-HIV+ HOPE Act kidney-transplant recipients | Tatianna Travieso, Hannah Stadtler, Naseem Alavian, Feng Gao, Mary Klotman, Cameron Robert Wolfe, Maria Blasi | |
| 2024-10-16 | Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation | Jonathan Bohlen, Ivan Bagarić, Taja Vatovec, Masato Ogishi, Syed F. Ahmed, Axel Cederholm, Lori Buetow, Steicy Sobrino, Corentin Le Floc’h, Carlos A. Arango-Franco, Luis Seabra, Marine Michelet, Federica Barzaghi, Davide Leardini, Francesco Saettini, Fran | |
| 2024-10-16 | Transcript splicing optimizes the thymic self-antigen repertoire to suppress autoimmunity | Ryunosuke Muro, Takeshi Nitta, Sachiko Nitta, Masayuki Tsukasaki, Tatsuo Asano, Kenta Nakano, Tadashi Okamura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi | |
| 2024-10-16 | PRMT5: splicing up tolerance | Rathan Kumar, Parvathi Ranganathan | |
| 2024-10-16 | Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders | Rachel L. Kember, Christal N. Davis, Kyra L. Feuer, Henry R. Kranzler | |
| 2024-10-16 | Cannabis use disorder: from neurobiology to treatment | Bernard Le Foll, Victor M. Tang, Sergio Rueda, Leanne V. Trick, Isabelle Boileau | |
| 2024-10-16 | Epigenetic therapies targeting histone lysine methylation: complex mechanisms and clinical challenges | Sarah Gold, Ali Shilatifard | |
| 2024-10-16 | Metabolic rewiring during bone development underlies tRNA m7G–associated primordial dwarfism | Qiwen Li, Shuang Jiang, Kexin Lei, Hui Han, Yaqian Chen, Weimin Lin, Qiuchan Xiong, Xingying Qi, Xinyan Gan, Rui Sheng, Yuan Wang, Yarong Zhang, Jieyi Ma, Tao Li, Shuibin Lin, Chenchen Zhou, Demeng Chen, Quan Yuan | |
| 2024-10-16 | Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria | Jinren Zhou, Jian Gu, Qufei Qian, Yigang Zhang, Tianning Huang, Xiangyu Li, Zhuoqun Liu, Qing Shao, Yuan Liang, Lei Qiao, Xiaozhang Xu, Qiuyang Chen, Zibo Xu, Yu Li, Ji Gao, Yufeng Pan, Yiming Wang, Roderick O’Connor, Keli L. Hippen, Ling Lu, Bruce R. Bla | |
| 2024-10-16 | B cell–based therapy produces antibodies that inhibit glioblastoma growth | Si Wang, Brandyn A. Castro, Joshua L. Katz, Victor Arrieta, Hinda Najem, Gustavo I. Vazquez-Cervantes, Hanxiao Wan, Ian E. Olson, David Hou, Mark Dapash, Leah K. Billingham, Tzu-yi Chia, Chao Wei, Aida Rashidi, Leonidas C. Platanias, Kathleen McCortney, C | |
| 2024-10-16 | Distinguishing between help and harm: Helper T cell subsets and immune-related adverse events | Alexandra M. Haugh, Adil I. Daud | |
| 2024-10-16 | An emerging multi-omic understanding of the genetics of opioid addiction | Eric O. Johnson, Heidi S. Fisher, Kyle A. Sullivan, Olivia Corradin, Sandra Sanchez-Roige, Nathan C. Gaddis, Yasmine N. Sami, Alice Townsend, Erica Teixeira Prates, Mirko Pavicic, Peter Kruse, Elissa J. Chesler, Abraham A. Palmer, Vanessa Troiani, Jason A | |
| 2024-10-16 | Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures | Chester J. Kao, Soren Charmsaz, Stephanie L. Alden, Madelena Brancati, Howard L. Li, Aanika Balaji, Kabeer Munjal, Kathryn Howe, Sarah Mitchell, James Leatherman, Ervin Griffin, Mari Nakazawa, Hua-Ling Tsai, Ludmila Danilova, Chris Thoburn, Jennifer Gizzi | |
| 2024-10-02 | Sleepless nights and social plights: medial septum GABAergic hyperactivity in a neuroligin 3–deficient autism model | Claire E. Cho, Dahee Jung, Reesha R. Patel | |
| 2024-10-02 | Clonal hematopoiesis and atherosclerosis | Ohad Oren, Aeron M. Small, Peter Libby | |
| 2024-10-02 | Pediatric glioma immune profiling identifies TIM3 as a therapeutic target in BRAF fusion pilocytic astrocytoma | Shashwat Tripathi, Hinda Najem, Corey Dussold, Sebastian Pacheco, Ruochen Du, Moloud Sooreshjani, Lisa Hurley, James P. Chandler, Roger Stupp, Adam M. Sonabend, Craig M. Horbinski, Rimas V. Lukas, Joanne Xiu, Giselle Lopez, Theodore P. Nicolaides, Valerie | |
| 2024-10-02 | Distinct landscape and clinical implications of therapy-related clonal hematopoiesis | Koichi Takahashi, Daisuke Nakada, Margaret Goodell | |
| 2024-10-02 | The expanding application of antisense oligonucleotides to neurodegenerative diseases | Charlotte J. Sumner, Timothy M. Miller | |
| 2024-10-02 | Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression | Jade Bath, Elisabet Bjånes, Cengiz Goekeri, Jeff Hsiao, Deniz Uzun, Geraldine Nouailles, Victor Nizet, Katharina Ribbeck | |
| 2024-10-02 | Intertwining clonality and resistance: Staphylococcus aureus in the antibiotic era | Henry F. Chambers, Vance G. Fowler Jr | |
| 2024-10-02 | The first century of JCI and beyond | Elizabeth M. McNally | |
| 2024-10-02 | The emergence of clonal hematopoiesis as a disease determinant | Kenneth Walsh | |
| 2024-10-02 | The arc of discovery, from the description of cystic fibrosis to effective treatments | Michael J. Welsh | |
| 2024-10-02 | Toward a better understanding of chronic hepatitis B virus infection | Barbara Rehermann | |
| 2024-10-02 | The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression | Ji Hye Jun, Kuo Du, Rajesh Kumar Dutta, Raquel Maeso-Diaz, Seh Hoon Oh, Liuyang Wang, Guannan Gao, Ana Ferreira, Jon Hill, Steven S. Pullen, Anna Mae Diehl | |
| 2024-10-02 | Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer | Xiaolin Zhu, Tatyanah Farsh, Daniël Vis, Ivan Yu, Haolong Li, Tianyi Liu, Martin Sjöström, Raunak Shrestha, Jeroen Kneppers, Tesa Severson, Meng Zhang, Arian Lundberg, Thaidy Moreno Rodriguez, Alana S. Weinstein, Adam Foye, Niven Mehra, Rahul R. Aggarwal, | |
| 2024-10-02 | Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli | Xiuyu Lin, Weicheng Chen, Guilin Yang, Jiazhu Zhang, Huilin Wang, Zeyu Liu, Ying Xi, Tao Ren, Bo Liu, Pengfei Sui | |
| 2024-10-02 | Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells | Chia-Lin Chen, Hidekazu Tsukamoto, Jian-Chang Liu, Claudine Kashiwabara, Douglas Feldman, Linda Sher, Steven Dooley, Samuel W. French, Lopa Mishra, Lydia Petrovic, Joseph H. Jeong, Keigo Machida | |
| 2024-10-02 | 2024 Lasker Award Recipient Zhijian Chen elucidates how DNA stimulates immunity | Amy B. Heimberger | |
| 2024-10-02 | Joel Habener, Svetlana Mojsov, and Lotte Bjerre Knudsen awarded Lasker prize for pioneering work on GLP-1 | Hossein Ardehali | |
| 2024-10-02 | IFN-γ and YAP lead epithelial cells astray after severe respiratory infection | Bradley E. Hiller, Joseph P. Mizgerd | |
| 2024-10-02 | Autism-associated neuroligin 3 deficiency in medial septum causes social deficits and sleep loss in mice | Haiyan Sun, Yu Shen, Pengtao Ni, Xin Liu, Yan Li, Zhentong Qiu, Jiawen Su, Yihan Wang, Miao Wu, Xiangxi Kong, Jun-Li Cao, Wei Xie, Shuming An | |
| 2024-10-02 | Neurosymptomatic HIV-1 CSF escape is associated with replication in CNS T cells and inflammation | Laura P. Kincer, Ameet Dravid, Mattia Trunfio, Andrea Calcagno, Shuntai Zhou, Riccardo Vercesi, Serena Spudich, Magnus Gisslen, Richard W. Price, Paola Cinque, Sarah B. Joseph | |
| 2024-10-02 | Ciliary localization of GPR75 promotes fat accumulation in mice | Marcelo Chávez, Anushweta Asthana, Peter K. Jackson | |
| 2024-10-02 | Single-cell multiomic analysis identifies macrophage subpopulations in promoting cardiac repair | Mingzhu Fu, Shengtao Jia, Longhui Xu, Xin Li, Yufang Lv, Yulong Zhong, Shanshan Ai | |
| 2024-10-02 | Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing | Omid Sadeghi-Alavijeh, Melanie M.Y. Chan, Gabriel T. Doctor, Catalin D. Voinescu, Alexander Stuckey, Athanasios Kousathanas, Alexander T. Ho, Horia C. Stanescu, Detlef Bockenhauer, Richard N. Sandford, Adam P. Levine, Daniel P. Gale | |
| 2024-10-02 | Central regulation of feeding and body weight by ciliary GPR75 | Yiao Jiang, Yu Xun, Zhao Zhang | |
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