| 2024-09-19 |
Deep humoral profiling coupled to interpretable machine learning unveils diagnostic markers and pathophysiology of schistosomiasis | Science Translational Medicine |
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| 2024-09-19 |
Perfusion imaging metrics after acute traumatic spinal cord injury are associated with injury severity in rats and humans | Science Translational Medicine |
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| 2024-09-19 |
ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome | Science Translational Medicine |
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| 2024-09-19 |
Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade | Science Translational Medicine |
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| 2024-09-19 |
Preschool-age children maintain a distinct memory CD4+ T cell and memory B cell response after SARS-CoV-2 infection | Science Translational Medicine |
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| 2024-09-19 |
A deep intronic splice–altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion | Science Translational Medicine |
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| 2024-09-12 |
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging | Science Translational Medicine |
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| 2024-09-12 |
A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories | Science Translational Medicine |
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| 2024-09-12 |
Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models | Science Translational Medicine |
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| 2024-09-12 |
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis | Science Translational Medicine |
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| 2024-09-12 |
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML | Science Translational Medicine |
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| 2024-09-12 |
Erratum for the Research Article “Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70” by B. Brook et al. | Science Translational Medicine |
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| 2024-09-05 |
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months | Science Translational Medicine |
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| 2024-09-05 |
PTPRT loss enhances anti–PD-1 therapy efficacy by regulation of STING pathway in non–small cell lung cancer | Science Translational Medicine |
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| 2024-09-05 |
A skin-interfaced microfluidic platform supports dynamic sweat biochemical analysis during human exercise | Science Translational Medicine |
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| 2024-09-05 |
Inhibition of CCL7 improves endothelial dysfunction and vasculopathy in mouse models of diabetes mellitus | Science Translational Medicine |
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| 2024-09-05 |
Precision adjuvants for pediatric vaccines | Science Translational Medicine |
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| 2024-08-29 |
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer | Science Translational Medicine |
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| 2024-08-29 |
Activation and antitumor immunity of CD8+ T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid | Science Translational Medicine |
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| 2024-08-29 |
An autoimmune transcriptional circuit drives FOXP3+ regulatory T cell dysfunction | Science Translational Medicine |
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| 2024-08-29 |
Inhibiting endothelial Rhoj blocks profibrotic vascular intussusception and angiocrine factors to sustain lung regeneration | Science Translational Medicine |
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| 2024-08-29 |
Next-generation CAR T cell therapies for glioblastoma | Science Translational Medicine |
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| 2024-08-29 |
Erratum for the Research Article “MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells” by S. Perrin et al. | Science Translational Medicine |
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| 2024-08-22 |
Stress-induced eosinophil activation contributes to postoperative morbidity and mortality after lung resection | Science Translational Medicine |
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| 2024-08-22 |
Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease | Science Translational Medicine |
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| 2024-08-22 |
Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice | Science Translational Medicine |
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| 2024-08-22 |
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies | Science Translational Medicine |
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| 2024-08-22 |
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants | Science Translational Medicine |
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| 2024-08-15 |
Acyl-CoA binding protein for the experimental treatment of anorexia | Science Translational Medicine |
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| 2024-08-15 |
Natural killer cells promote neutrophil extracellular traps and restrain macular degeneration in mice | Science Translational Medicine |
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| 2024-08-15 |
Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model | Science Translational Medicine |
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| 2024-08-15 |
Development and preclinical validation of 2-deoxy 2-[18F]fluorocellobiose as an Aspergillus-specific PET tracer | Science Translational Medicine |
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| 2024-08-15 |
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier | Science Translational Medicine |
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| 2024-08-15 |
An identity crisis for lung cancer cells | Science Translational Medicine |
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| 2024-08-15 |
Erratum for the Research Article “A β-Arrestin–Biased Agonist of the Parathyroid Hormone Receptor (PTH1R) Promotes Bone Formation Independent of G Protein Activation” by D. Gesty-Palmer et al. | Science Translational Medicine |
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| 2024-08-08 |
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity | Science Translational Medicine |
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| 2024-08-08 |
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models | Science Translational Medicine |
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| 2024-08-08 |
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis | Science Translational Medicine |
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| 2024-08-08 |
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice | Science Translational Medicine |
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| 2024-08-08 |
Engineered exosomes with a photoinducible protein delivery system enable CRISPR-Cas–based epigenome editing in Alzheimer’s disease | Science Translational Medicine |
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| 2024-08-01 |
MGA deletion leads to Richter’s transformation by modulating mitochondrial OXPHOS | Science Translational Medicine |
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| 2024-08-01 |
Functional and epigenetic changes in monocytes from adults immunized with an AS01-adjuvanted vaccine | Science Translational Medicine |
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| 2024-08-01 |
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes | Science Translational Medicine |
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| 2024-08-01 |
A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates | Science Translational Medicine |
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| 2024-08-01 |
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients | Science Translational Medicine |
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| 2024-08-01 |
Neural landscape is associated with functional outcomes in irradiated patients with oropharyngeal squamous cell carcinoma | Science Translational Medicine |
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| 2024-08-01 |
Make it a combo | Science Translational Medicine |
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| 2024-08-01 |
Erratum for the Research Article “Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas” by N. Kanaya et al. | Science Translational Medicine |
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| 2024-07-25 |
Primary cilia mediate skeletogenic BMP and Hedgehog signaling in heterotopic ossification | Science Translational Medicine |
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| 2024-07-25 |
Human iPSC–liver organoid transplantation reduces fibrosis through immunomodulation | Science Translational Medicine |
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| 2024-07-25 |
Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models | Science Translational Medicine |
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| 2024-07-25 |
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease | Science Translational Medicine |
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| 2024-07-25 |
Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70 | Science Translational Medicine |
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| 2024-07-25 |
Improving vaccine equity by increasing vaccine thermostability | Science Translational Medicine |
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| 2024-07-18 |
Extracellular vesicle–packaged PIAT from cancer-associated fibroblasts drives neural remodeling by mediating m5C modification in pancreatic cancer mouse models | Science Translational Medicine |
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| 2024-07-18 |
Knockdown of swine leukocyte antigen expression in porcine lung transplants enables graft survival without immunosuppression | Science Translational Medicine |
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| 2024-07-18 |
Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction | Science Translational Medicine |
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| 2024-07-18 |
Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19 | Science Translational Medicine |
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| 2024-07-18 |
Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming | Science Translational Medicine |
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| 2024-07-18 |
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al. | Science Translational Medicine |
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| 2024-07-11 |
Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities | Science Translational Medicine |
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| 2024-07-11 |
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models | Science Translational Medicine |
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| 2024-07-11 |
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system | Science Translational Medicine |
ulrischa |
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| 2024-07-11 |
An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis | Science Translational Medicine |
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| 2024-07-11 |
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation | Science Translational Medicine |
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| 2024-07-04 |
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections | Science Translational Medicine |
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| 2024-07-04 |
Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection | Science Translational Medicine |
thenerdhead |
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| 2024-07-04 |
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models | Science Translational Medicine |
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| 2024-07-04 |
Lupus IgA1 autoantibodies synergize with IgG to enhance plasmacytoid dendritic cell responses to RNA-containing immune complexes | Science Translational Medicine |
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| 2024-07-04 |
Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice | Science Translational Medicine |
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| 2024-07-04 |
A nose for tau | Science Translational Medicine |
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| 2024-06-27 |
TRPML1 triggers ferroptosis defense and is a potential therapeutic target in AKT-hyperactivated cancer | Science Translational Medicine |
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| 2024-06-27 |
Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency | Science Translational Medicine |
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| 2024-06-27 |
Proteomic analysis of Alzheimer’s disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment | Science Translational Medicine |
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| 2024-06-27 |
AZD3152 neutralizes SARS-CoV-2 historical and contemporary variants and is protective in hamsters and well tolerated in adults | Science Translational Medicine |
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| 2024-06-27 |
MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells | Science Translational Medicine |
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| 2024-06-27 |
New government drug repurposing programs: Opportunities and uncertainties | Science Translational Medicine |
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| 2024-06-20 |
Topical JAK inhibition ameliorates EGFR inhibitor–induced rash in rodents and humans | Science Translational Medicine |
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| 2024-06-20 |
A subpopulation of tissue remodeling monocytes stimulates revascularization of the ischemic limb | Science Translational Medicine |
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| 2024-06-20 |
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release | Science Translational Medicine |
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| 2024-06-20 |
Inhibiting AGTR1 reduces AML burden and protects the heart from cardiotoxicity in mouse models | Science Translational Medicine |
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| 2024-06-20 |
A bioadhesive pacing lead for atraumatic cardiac monitoring and stimulation in rodent and porcine models | Science Translational Medicine |
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| 2024-06-13 |
Microglia promote maladaptive plasticity in autonomic circuitry after spinal cord injury in mice | Science Translational Medicine |
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| 2024-06-13 |
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia | Science Translational Medicine |
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| 2024-06-13 |
Prolonged xenokidney graft survival in sensitized NHP recipients by expression of multiple human transgenes in a triple knockout pig | Science Translational Medicine |
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| 2024-06-13 |
Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation | Science Translational Medicine |
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| 2024-06-13 |
Prior Covid infection may protect against common cold |
vagabund |
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| 2024-06-06 |
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response | Science Translational Medicine |
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| 2024-06-06 |
Replenishing IRAK-M expression in retinal pigment epithelium attenuates outer retinal degeneration | Science Translational Medicine |
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| 2024-06-06 |
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics | Science Translational Medicine |
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| 2024-06-06 |
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration | Science Translational Medicine |
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| 2024-06-06 |
Muscle-bone cross-talk through the FNIP1-TFEB-IGF2 axis is associated with bone metabolism in human and mouse | Science Translational Medicine |
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| 2024-05-30 |
An ALK2 inhibitor, BLU-782, prevents heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva | Science Translational Medicine |
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| 2024-05-30 |
Functional ultrasound imaging of human brain activity through an acoustically transparent cranial window | Science Translational Medicine |
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| 2024-05-30 |
Primary exposure to Zika virus is linked with increased risk of symptomatic dengue virus infection with serotypes 2, 3, and 4, but not 1 | Science Translational Medicine |
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| 2024-05-30 |
Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma | Science Translational Medicine |
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| 2024-05-30 |
Erratum for the Research Article “Alpelisib administration reduced lymphatic malformations in a mouse model and in patients” by F. Delestre et al. | Science Translational Medicine |
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| 2024-05-24 |
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders | Science Translational Medicine |
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| 2024-05-23 |
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses | Science Translational Medicine |
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| 2024-05-23 |
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 6 | Science Translational Medicine |
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