| 2024-08-21 |
Hyd/UBR5 defines a tumor suppressor pathway that links Polycomb repressive complex to regulated protein degradation in tissue growth control and tumorigenesis [Research Papers] |
Wen, P., Lei, H., Deng, H., Deng, S., Rodriguez Tirado, C., Wang, M., Mu, P., Zheng, Y., Pan, D. |
|
| 2024-08-21 |
Corrigendum: Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms [Errata] |
Rohde, M., Daugaard, M., Jensen, M. H., Helin, K., Nylandsted, J., Jäättelä, M. |
|
| 2024-08-21 |
A developmental mechanism to regulate alternative polyadenylation in an adult stem cell lineage [Research Papers] |
Gallicchio, L., Matias, N. R., Morales-Polanco, F., Nava, I., Stern, S., Zeng, Y., Fuller, M. T. |
|
| 2024-08-21 |
Tolerance thresholds underlie responses to DNA damage during germline development [Research Papers] |
Jansen, G., Gebert, D., Kumar, T. R., Simmons, E., Murphy, S., Teixeira, F. K. |
|
| 2024-08-21 |
SUMO promotes DNA repair protein collaboration to support alternative telomere lengthening in the absence of PML [Research Papers] |
Zhao, R., Xu, M., Yu, X., Wondisford, A. R., Lackner, R. M., Salsman, J., Dellaire, G., Chenoweth, D. M., O'Sullivan, R. J., Zhao, X., Zhang, H. |
|
| 2024-08-21 |
What goes up must come down: off switches for regulatory RNAs [Reviews] |
McJunkin, K., Gottesman, S. |
|
| 2024-08-21 |
Comparing the roles of sex chromosome-encoded protein homologs in gene regulation [Reviews] |
Lavorando, E., Owens, M. C., Liu, K. F. |
|
| 2024-07-19 |
Tert-expressing cells contribute to salivary gland homeostasis and tissue regeneration after radiation therapy [Research Papers] |
Guan, L., Viswanathan, V., Jiang, Y., Vijayakumar, S., Cao, H., Zhao, J., Colburg, D. R. C., Neuhöfer, P., Zhang, Y., Wang, J., Xu, Y., Laseinde, E. E., Hildebrand, R., Rahman, M., Frock, R., Kong, C., Beachy, P. A., Artandi, S., Le, Q.-T. |
|
| 2024-07-19 |
Corrigendum: The evolutionary turnover of recombination hot spots contributes to speciation in mice [Errata] |
Smagulova, F., Brick, K., Pu, Y., Camerini-Otero, R. D., Petukhova, G. V. |
|
| 2024-07-19 |
ChAHP2 and ChAHP control diverse retrotransposons by complementary activities [Research Papers] |
Ahel, J., Pandey, A., Schwaiger, M., Mohn, F., Basters, A., Kempf, G., Andriollo, A., Kaaij, L., Hess, D., Bühler, M. |
|
| 2024-07-19 |
Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-{kappa}B p50-I{kappa}B{zeta} pathway [Research Papers] |
Daly, A. E., Yeh, G., Soltero, S., Smale, S. T. |
|
| 2024-07-19 |
Structural and biochemical analyses of the nuclear I{kappa}B{zeta} protein in complex with the NF-{kappa}B p50 homodimer [Research Communications] |
Zhu, N., Rogers, W. E., Heidary, D. K., Huxford, T. |
|
| 2024-07-19 |
RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity [Reviews] |
Chromatin and Gene Expression, Post-transcriptional Control ‧ Luna, R., Gomez-Gonzalez, B., Aguilera, A. |
|
| 2024-07-19 |
Epigenetic modulators provide a path to understanding disease and therapeutic opportunity [Reviews] |
Honer, M. A., Ferman, B. I., Gray, Z. H., Bondarenko, E. A., Whetstine, J. R. |
|
| 2024-06-26 |
Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis [Research Papers] |
Kotb, N. M., Ulukaya, G., Chavan, A., Nguyen, S. C., Proskauer, L., Joyce, E. F., Hasson, D., Jagannathan, M., Rangan, P. |
|
| 2024-06-26 |
Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation [Research Papers] |
Crain, A. T., Butler, M. B., Hill, C. A., Huynh, M., McGinty, R. K., Duronio, R. J. |
|
| 2024-06-26 |
A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate [Research Papers] |
Chavan, A., Isenhart, R., Nguyen, S. C., Kotb, N. M., Harke, J., Sintsova, A., Ulukaya, G., Uliana, F., Ashiono, C., Kutay, U., Pegoraro, G., Rangan, P., Joyce, E. F., Jagannathan, M. |
|
| 2024-06-26 |
Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development [Research Papers] |
Clark, J. F., Soriano, P. |
|
| 2024-06-26 |
Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues [Research Papers] |
Sala, A. J., Grant, R. A., Imran, G., Morton, C., Brielmann, R. M., Gorgon, S., Watts, J., Bott, L. C., Morimoto, R. I. |
|
| 2024-06-26 |
Glioblastoma microenvironment--from biology to therapy [Reviews] |
Cancer and Disease Models, Neurobiology ‧ Read, R. D., Tapp, Z. M., Rajappa, P., Hambardzumyan, D. |
|
| 2024-06-26 |
Beyond histones: the elusive substrates of chromatin regulators [Outlook] |
Chromatin and Gene Expression ‧ Mannervik, M. |
|
| 2024-05-22 |
Corrigendum: Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination [Errata] |
Steinfeld, J. B., Belan, O., Kwon, Y., Terakawa, T., Al-Zain, A., Smith, M. J., Crickard, J. B., Qi, Z., Zhao, W., Rothstein, R., Symington, L. S., Sung, P., Boulton, S. J., Greene, E. C. |
|
| 2024-05-22 |
Corrigendum: miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma [Errata] |
Kouri, F. M., Hurley, L. A., Daniel, W. L., Day, E. S., Hua, Y., Hao, L., Peng, C.-Y., Merkel, T. J., Queisser, M. A., Ritner, C., Zhang, H., James, C. D., Sznajder, J. I., Chin, L., Giljohann, D. A., Kessler, J. A., Peter, M. E., Mirkin, C. A., Stegh, A. |
|
| 2024-05-22 |
H2A.Z chaperones converge on E2F target genes for melanoma cell proliferation [Research Papers] |
Jostes, S., Vardabasso, C., Dong, J., Carcamo, S., Singh, R., Phelps, R., Meadows, A., Grossi, E., Hasson, D., Bernstein, E. |
|
| 2024-05-22 |
Intron lariat spliceosomes convert lariats to true circles: implications for intron transposition [Research Papers] |
Ares, M., Igel, H., Katzman, S., Donohue, J. P. |
|
| 2024-05-22 |
Oct4 redox sensitivity potentiates reprogramming and differentiation [Research Papers] |
Shen, Z., Wu, Y., Manna, A., Yi, C., Cairns, B. R., Evason, K. J., Chandrasekharan, M. B., Tantin, D. |
|
| 2024-05-22 |
The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons [Research Papers] |
Xiao, W., Halabi, R., Lin, C.-H., Nazim, M., Yeom, K.-H., Black, D. L. |
|
| 2024-05-22 |
An unexpected path for Malat1 in neurons: trafficking out of the nucleus for translation [Outlook] |
Chromatin and Gene Expression ‧ Wright, B. W., Wilusz, J. E. |
|
| 2024-04-18 |
Corrigendium: Effects of RAS on the genesis of embryonal rhabdomyosarcoma [Errata] |
Langenau, D. M., Keefe, M. D., Storer, N. Y., Guyon, J. R., Kutok, J. L., Le, X., Goessling, W., Neuberg, D. S., Kunkel, L. M., Zon, L. I. |
|
| 2024-04-18 |
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype [Research Papers] |
Nuechterlein, N., Shelbourn, A., Szulzewsky, F., Arora, S., Casad, M., Pattwell, S., Merino-Galan, L., Sulman, E., Arowa, S., Alvinez, N., Jung, M., Brown, D., Tang, K., Jackson, S., Stoica, S., Chittaboina, P., Banasavadi-Siddegowda, Y. K., Wirsching, H. |
|
| 2024-04-18 |
A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies [Research Papers] |
Freie, B., Carroll, P. A., Varnum-Finney, B. J., Ramsey, E. L., Ramani, V., Bernstein, I., Eisenman, R. N. |
|
| 2024-04-18 |
NFATC2IP is a mediator of SUMO-dependent genome integrity [Research Papers] |
Cho, T., Hoeg, L., Setiaputra, D., Durocher, D. |
|
| 2024-04-18 |
WRN exonuclease imparts high fidelity on translesion synthesis by Y family DNA polymerases [Research Papers] |
Yoon, J.-H., Sellamuthu, K., Prakash, L., Prakash, S. |
|
| 2024-04-18 |
Protein domains of low sequence complexity--dark matter of the proteome [Perspectives] |
Cell Biology ‧ McKnight, S. L. |
|
| 2023-08-18 |
Cell type-specific role of CBX2 and its disordered region in spermatogenesis [Research Papers] |
Kim, J. J., Steinson, E. R., Lau, M. S., de Rooij, D. G., Page, D. C., Kingston, R. E. |
|
| 2023-08-18 |
Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals [Research Papers] |
Jones, B. T., Han, J., Zhang, H., Hammer, R. E., Evers, B. M., Rakheja, D., Acharya, A., Mendell, J. T. |
|
| 2023-08-18 |
Delineation of two multi-invasion-induced rearrangement pathways that differently affect genome stability [Research Papers] |
Reitz, D., Djeghmoum, Y., Watson, R. A., Rajput, P., Argueso, J. L., Heyer, W.-D., Piazza, A. |
|
| 2023-08-18 |
RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils [Research Papers] |
Zezulin, A. U., Yen, D., Ye, D., Howell, E. D., Bresciani, E., Diemer, J., Ren, J.-g., Ahmad, M. H., Castilla, L. H., Touw, I. P., Minn, A. J., Tong, W., Liu, P. P., Tan, K., Yu, W., Speck, N. A. |
|
| 2023-08-18 |
Dynamic nucleosome remodeling mediated by YY1 underlies early mouse development [Research Papers] |
Sakamoto, M., Abe, S., Miki, Y., Miyanari, Y., Sasaki, H., Ishiuchi, T. |
|
| 2023-08-18 |
Histone bivalency regulates the timing of cerebellar granule cell development [Research Papers] |
Mätlik, K., Govek, E.-E., Paul, M. R., Allis, C. D., Hatten, M. E. |
|
| 2023-08-18 |
CST-Pol{alpha}/Primase: the second telomere maintenance machine [Reviews] |
Cell Cycle and DNA Replication, Chromatin and Gene Expression ‧ Cai, S. W., de Lange, T. |
|
| 2023-07-19 |
Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface [Research Papers] |
Liu, K., Grasso, E. M., Pu, S., Zou, M., Liu, S., Eliezer, D., Keeney, S. |
|
| 2023-07-19 |
Evolutionary conservation of the structure and function of meiotic Rec114-Mei4 and Mer2 complexes [Research Papers] |
Daccache, D., De Jonge, E., Liloku, P., Mechleb, K., Haddad, M., Corthaut, S., Sterckx, Y. G.- J., Volkov, A. N., Claeys Bouuaert, C. |
|
| 2023-07-19 |
Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions [Research Papers] |
Bonneau, F., Basquin, J., Steigenberger, B., Schäfer, T., Schäfer, I. B., Conti, E. |
|
| 2023-07-19 |
Major {beta} cell-specific functions of NKX2.2 are mediated via the NK2-specific domain [Research Papers] |
Abarinov, V., Levine, J. A., Churchill, A. J., Hopwood, B., Deiter, C. S., Guney, M. A., Wells, K. L., Schrunk, J. M., Guo, Y., Hammelman, J., Gifford, D. K., Magnuson, M. A., Wichterle, H., Sussel, L. |
|
| 2023-07-19 |
Translational regulation by uORFs and start codon selection stringency [Reviews] |
Translation ‧ Dever, T. E., Ivanov, I. P., Hinnebusch, A. G. |
|
| 2023-07-19 |
Circadian mechanisms in adipose tissue bioenergetics and plasticity [Reviews] |
Molecular Physiology and Metabolism ‧ Hepler, C., Bass, J. |
|
| 2023-07-19 |
Differential use of the Nkx2.2 NK2 domain in developing pancreatic islets and neurons [Outlook] |
Development, Chromatin and Gene Expression ‧ Seymour, P. A., Serup, P. |
|
| 2023-06-06 |
Corrigendum: Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells [Errata] |
Soares, M. A. F., Soares, D. S., Teixeira, V., Heskol, A., Bressan, R. B., Pollard, S. M., Oliveira, R. A., Castro, D. S. |
|
| 2023-06-06 |
Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation [Research Papers] |
Yang, G., Xin, Q., Feng, I., Wu, D., Dean, J. |
|
| 2023-06-06 |
Butt-seq: a new method for facile profiling of transcription [Resource/Methodology] |
Yu, A. D., Rosbash, M. |
|
| 2023-06-06 |
Long ant life span is maintained by a unique heat shock factor [Research Papers] |
Glastad, K. M., Roessler, J., Gospocic, J., Bonasio, R., Berger, S. L. |
|
| 2023-06-06 |
Role of the proline-rich disordered domain of DROSHA in intronic microRNA processing [Research Papers] |
Son, S., Kim, B., Yang, J., Kim, V. N. |
|
| 2023-06-06 |
Analysis of the Drosophila and human DPR elements reveals a distinct human variant whose specificity can be enhanced by machine learning [Research Communications] |
Vo ngoc, L., Rhyne, T. E., Kadonaga, J. T. |
|
| 2023-06-06 |
RNA granules: functional compartments or incidental condensates? [Reviews] |
Chromatin and Gene Expression ‧ Putnam, A., Thomas, L., Seydoux, G. |
|
| 2023-06-06 |
Designer genes courtesy of artificial intelligence [Outlook] |
Genomics, Chromatin and Gene Expression ‧ Hoffmann, A. |
|
| 2023-04-25 |
Noncatalytic regulation of 18S rRNA methyltransferase DIMT1 in acute myeloid leukemia [Research Papers] |
Gonskikh, Y., Stoute, J., Shen, H., Budinich, K., Pingul, B., Schultz, K., Elashal, H., Marmorstein, R., Shi, J., Liu, K. F. |
|
| 2023-04-25 |
A change in biophysical properties accompanies heterochromatin formation in mouse embryos [Research Papers] |
Guthmann, M., Qian, C., Gialdini, I., Nakatani, T., Ettinger, A., Schauer, T., Kukhtevich, I., Schneider, R., Lamb, D. C., Burton, A., Torres-Padilla, M.-E. |
|
| 2023-04-25 |
Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma [Research Papers] |
Zacarias-Fluck, M. F., Masso-Valles, D., Giuntini, F., Gonzalez-Larreategui, I., Kaur, J., Casacuberta-Serra, S., Jauset, T., Martinez-Martin, S., Martin-Fernandez, G., Serrano del Pozo, E., Foradada, L., Grueso, J., Nonell, L., Beaulieu, M.-E., Whitfield |
|
| 2023-04-25 |
Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation [Research Papers] |
Liu, T.-T., Ou, F., Belk, J. A., Bagadia, P., Anderson, D. A., Durai, V., Yao, W., Satpathy, A. T., Murphy, T. L., Murphy, K. M. |
|
| 2023-04-25 |
A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p [Research Papers] |
Boardman, K., Xiang, S., Chatterjee, F., Mbonu, U., Guacci, V., Koshland, D. |
|
| 2023-04-25 |
Genetic cold cases: lessons from solving complex congenital limb disorders [Reviews] |
Molecular Physiology and Metabolism, Genomics, Cancer and Disease Models ‧ Andrey, G., Duboule, D. |
|
| 2023-04-25 |
Chromosome organization by fine-tuning an ATPase [Outlook] |
Chromatin and Gene Expression ‧ Massari, L. F., Marston, A. L. |
|
| 2023-03-31 |
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation [Research Papers] |
Paun, O., Tan, Y. X., Patel, H., Strohbuecker, S., Ghanate, A., Cobolli-Gigli, C., Llorian Sopena, M., Gerontogianni, L., Goldstone, R., Ang, S.-L., Guillemot, F., Dias, C. |
|
| 2023-03-31 |
ALL-tRNAseq enables robust tRNA profiling in tissue samples [Resource/Methodology] |
Scheepbouwer, C., Aparicio-Puerta, E., Gomez-Martin, C., Verschueren, H., van Eijndhoven, M., Wedekind, L. E., Giannoukakos, S., Hijmering, N., Gasparotto, L., van der Galien, H. T., van Rijn, R. S., Aronica, E., Kibbelaar, R., Heine, V. M., Wesseling, P. |
|
| 2023-03-31 |
ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease [Research Papers] |
Song, S., Su, Z., Kon, N., Chu, B., Li, H., Jiang, X., Luo, J., Stockwell, B. R., Gu, W. |
|
| 2023-03-31 |
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein [Research Papers] |
Norris, M. L., Mendell, J. T. |
|
| 2023-03-31 |
Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies [Research Papers] |
Adell, M. A. Y., Klockner, T. C., Höfler, R., Wallner, L., Schmid, J., Markovic, A., Martyniak, A., Campbell, C. S. |
|
| 2023-03-31 |
SPOC domain proteins in health and disease [Reviews] |
Chromatin and Gene Expression ‧ Appel, L.-M., Benedum, J., Engl, M., Platzer, S., Schleiffer, A., Strobl, X., Slade, D. |
|
| 2023-03-31 |
It's complicated: the interplay of Kif1c mRNA localization in cell protrusions, assembly of protein binding partners on the KIF1C protein, and cell migration [Outlook] |
Cell Biology, Post-transcriptional Control ‧ Sarfraz, N., Braselmann, E. |
|
| 2023-03-17 |
Enzymatic reactions of AGO4 in RNA-directed DNA methylation: siRNA duplex loading, passenger strand elimination, target RNA slicing, and sliced target retention [Research Papers] |
Wang, F., Huang, H.-Y., Huang, J., Singh, J., Pikaard, C. S. |
|
| 2023-03-17 |
PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection [Research Papers] |
Ceppi, I., Cannavo, E., Bret, H., Camarillo, R., Vivalda, F., Thakur, R. S., Romero-Franco, A., Sartori, A. A., Huertas, P., Guerois, R., Cejka, P. |
|
| 2023-03-17 |
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma [Research Papers] |
Mitchell, K., Sprowls, S. A., Arora, S., Shakya, S., Silver, D. J., Goins, C. M., Wallace, L., Roversi, G., Schafer, R. E., Kay, K., Miller, T. E., Lauko, A., Bassett, J., Kashyap, A., D'Amato Kass, J., Mulkearns-Hubert, E. E., Johnson, S., Alvarado, J., |
|
| 2023-03-17 |
An FGF timer for zygotic genome activation [Research Communications] |
Treen, N., Chavarria, E., Weaver, C. J., Brangwynne, C. P., Levine, M. |
|
| 2023-03-17 |
Balancing act of a leading strand DNA polymerase-specific domain and its exonuclease domain promotes genome-wide sister replication fork symmetry [Research Communications] |
Meng, X., Claussin, C., Regan-Mochrie, G., Whitehouse, I., Zhao, X. |
|
| 2023-03-17 |
The evolving tale of Pol2 function [Outlook] |
DNA Recombination and Repair, Chromatin and Gene Expression ‧ Gallitto, M., Zhang, Z. |
|
| 2023-03-17 |
Broken up but still living together: how ARGONAUTE's retention of cleaved fragments explains its role during chromatin modification [Outlook] |
Chromatin and Gene Expression, Post-transcriptional Control ‧ Edwards, S. A., Slotkin, R. K. |
|
| 2023-03-02 |
Apoptosis, autophagy, and cancer: the critical role Genes & Development played in paradigm shifts [Essays] |
White, E. |
|
| 2023-03-02 |
Terri Grodzicker: 35 years of shaping scientific publishing and communication [Essays] |
Grosschedl, R. |
|
| 2023-03-02 |
My pearl anniversary with Genes & Development, 30 years on... [Essays] |
Soriano, P. |
|
| 2023-03-02 |
Totipotency, development, and chromatin [Essays] |
Torres-Padilla, M.-E. |
|
| 2023-03-02 |
Letter to the Editor [Essays] |
Proudfoot, N. J. |
|
| 2023-03-02 |
Terri Grodzicker: Editor, leader, and friend [Essays] |
Shilatifard, A. |
|
| 2023-03-02 |
Rate my Editor [Essays] |
de Lange, T. |
|
| 2023-03-02 |
How do genomes encode developmental time? [Essays] |
Raimundo, J., Levine, M. |
|
| 2023-03-02 |
You can be an editor too! [Essays] |
Herr, W. |
|
| 2023-03-02 |
Terri Grodzicker: advocate and influencer of impactful science [Essays] |
Berger, S. L. |
|
| 2023-03-02 |
TG and G&D: some thoughts and reminiscences [Essays] |
Mathews, M. B. |
|
| 2023-03-02 |
Terri and G&D: celebrating 50 years of enlightened scientific judgment [Essays] |
Tjian, R. |
|
| 2023-03-02 |
How Terri Grodzicker transformed Genes & Development [Essays] |
Prives, C. |
|
| 2023-03-02 |
Letters to the Editor [Essays] |
Kadonaga, J. T. |
|
| 2023-03-02 |
MYC through the lens of G&D [Essays] |
Eisenman, R. N. |
|
| 2023-03-02 |
Genes and my development [Essays] |
Lazar, M. A. |
|
| 2023-03-02 |
An Editor's rave review [Essays] |
Elledge, S. J. |
|
| 2023-03-02 |
Terri Grodzicker and the making of Genes & Development [Essays] |
Manley, J. |
|
| 2023-03-02 |
Legacy: a tribute to Terri Grodzicker of Genes & Development [Essays] |
Evans, R. M. |
|
| 2023-03-02 |
Terri Grodzicker: the quintessential scientist-Editor [Essays] |
Reinberg, D. |
|
| 2023-03-02 |
A tribute to Terri Grodzicker from an admirer [Essays] |
Fuchs, E. |
|
| 2023-03-02 |
Dr. Terri Grodzicker: leading Genes & Development through 35 years of rapidly advancing molecular biology research [Essays] |
Smale, S. T. |
|
| 2023-03-02 |
Making a journal great: an ode to Terri Grodzicker [Essays] |
Gasser, S. M. |
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