| 2020-03-20 |
Influence of sulfonated and diet-derived human milk oligosaccharides on the infant microbiome and immune markers [Immunology] |
Candice Quin, Sara D. Vicaretti, Nina A Mohtarudin, Alexander M. Garner, Deanna M. Vollman, Deanna L. Gibson, Wesley F. Zandberg |
|
| 2020-03-20 |
Correction: Vitamin and cofactor acquisition in apicomplexans: Synthesis versus salvage. [Additions and Corrections] |
Aarti Krishnan, Joachim Kloehn, Matteo Lunghi, Dominique Soldati-Favre |
|
| 2020-03-20 |
A previously identified apoptosis inhibitor iASPP confers resistance to chemotherapeutic drugs by suppressing senescence in cancer cells [Molecular Bases of Disease] |
Huayi Li, Wenxin Zhang, Kunming Zhao, Dong Zhao, Shanliang Zheng, Ying Hu |
|
| 2020-03-20 |
Melding the best of two worlds: Cecil Pickett's work on cellular oxidative stress and in drug discovery and development [Molecular Bases of Disease] |
Martin J. Spiering |
|
| 2020-03-20 |
Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP [Lipids] |
Yen-Chou Kuan, Yu Takahashi, Takashi Maruyama, Makoto Shimizu, Yoshio Yamauchi, Ryuichiro Sato |
|
| 2020-03-20 |
Self-control of vitamin K2 production captured in the crystal [Microbiology] |
Mickael Blaise, Laurent Kremer |
|
| 2020-03-20 |
Phosphoglycerol-type wall and lipoteichoic acids are enantiomeric polymers differentiated by the stereospecific glycerophosphodiesterase GlpQ [Microbiology] |
Axel Walter, Sandra Unsleber, Jeanine Rismondo, Ana Maria Jorge, Andreas Peschel, Angelika Grundling, Christoph Mayer |
|
| 2020-03-20 |
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays [Molecular Bases of Disease] |
Alex Crowe, Mark J. Henderson, Johnathon Anderson, Steven A. Titus, Alexey Zakharov, Anton Simeonov, Arjan Buist, Charlotte Delay, Diederik Moechars, John Q. Trojanowski, Virginia M.-Y. Lee, Kurt R. Brunden |
|
| 2020-03-20 |
The complex of outer-arm dynein light chain-1 and the microtubule-binding domain of the {gamma} heavy chain shows how axonemal dynein tunes ciliary beating [Protein Structure and Folding] |
Akiyuki Toda, Yosuke Nishikawa, Hideaki Tanaka, Toshiki Yagi, Genji Kurisu |
|
| 2020-03-20 |
Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome [Cell Biology] |
Ernesto Canalis, Tamar R. Grossman, Michele Carrer, Lauren Schilling, Jungeun Yu |
|
| 2020-03-20 |
Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery [Cell Biology] |
Kanika Dhawan, Naava Naslavsky, Steve Caplan |
|
| 2020-03-20 |
Structure-based group A streptococcal vaccine design: Helical wheel homology predicts antibody cross-reactivity among streptococcal M protein-derived peptides [Immunology] |
Michelle P. Aranha, Thomas A. Penfound, Jay A. Spencer, Rupesh Agarwal, Jerome Baudry, James B. Dale, Jeremy C. Smith |
|
| 2020-03-20 |
TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation [Neurobiology] |
Sabrina Semmler, Myriam Gagne, Pranav Garg, Sarah R. Pickles, Charlotte Baudouin, Emeline Hamon–Keromen, Laurie Destroismaisons, Yousra Khalfallah, Mathilde Chaineau, Elise Caron, Andrew N. Bayne, Jean–Francois Trempe, Neil R. Cashman, |
|
| 2020-03-20 |
The glutamic acid-rich-long C-terminal extension of troponin T has a critical role in insect muscle functions [Protein Synthesis and Degradation] |
Tianxin Cao, Alyson Sujkowski, Tyler Cobb, Robert J. Wessells, Jian-Ping Jin |
|
| 2020-03-20 |
A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry [Protein Structure and Folding] |
Janelle A. Hayes, Brendan J. Hilbert, Christl Gaubitz, Nicholas P. Stone, Brian A. Kelch |
|
| 2020-03-20 |
The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response [Metabolism] |
Evandro A. De-Souza, Felipe S. A. Pimentel, Ana Luiza F. V. De-Queiroz, Henrique Camara, Mikaella L. Felix-Formiga, Caio M. Machado, Silas Pinto, Antonio Galina, Marcelo A. Mori, Monica Montero-Lomeli, Claudio A. Masuda |
|
| 2020-03-20 |
The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2 [Cell Biology] |
Melany J. Wagner, Marilyn S. Hsiung, Gerald D. Gish, Rick D. Bagshaw, Sasha A. Doodnauth, Mohamed A. Soliman, Claus Jorgensen, Monika Tucholska, Robert Rottapel |
|
| 2020-03-20 |
Modulation of conformational equilibrium by phosphorylation underlies the activation of deubiquitinase A [Molecular Biophysics] |
Ashish Kabra, Efsita Rumpa, Ying Li |
|
| 2020-03-20 |
Transcriptome analysis reveals that the RNA polymerase-binding protein DksA1 has pleiotropic functions in Pseudomonas aeruginosa [Gene Regulation] |
Kyung Bae Min, Sang Sun Yoon |
|
| 2020-03-20 |
Tuning of pKa values activates substrates in flavin-dependent aromatic hydroxylases [Methods and Resources] |
Warintra Pitsawong, Pirom Chenprakhon, Taweesak Dhammaraj, Dheeradhach Medhanavyn, Jeerus Sucharitakul, Chanakan Tongsook, Willem J. H. van Berkel, Pimchai Chaiyen, Anne-Frances Miller |
|
| 2020-03-20 |
The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells [Molecular Bases of Disease] |
Jiri Stribny, Louise Thines, Antoine Deschamps, Philippe Goffin, Pierre Morsomme |
|
| 2020-03-20 |
Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks [Gene Regulation] |
Sandeep Singh, Karol Szlachta, Arkadi Manukyan, Heather M. Raimer, Manikarna Dinda, Stefan Bekiranov, Yuh-Hwa Wang |
|
| 2020-03-20 |
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular manganese [Cell Biology] |
Kyle J. Horning, Piyush Joshi, Rachana Nitin, Rekha C. Balachandran, Frank M. Yanko, Kwangho Kim, Plamen Christov, Michael Aschner, Gary A. Sulikowski, C. David Weaver, Aaron B. Bowman |
|
| 2020-03-20 |
Inorganic polyphosphate potentiates lipopolysaccharide-induced macrophage inflammatory response [Immunology] |
Toru Ito, Suguru Yamamoto, Keiichi Yamaguchi, Mami Sato, Yoshikatsu Kaneko, Shin Goto, Yuji Goto, Ichiei Narita |
|
| 2020-03-20 |
Putting the brakes on a myosin motor [Signal Transduction] |
Casey Eddington, Margaret A. Titus |
|
| 2020-03-20 |
Vitamin D receptor targets hepatocyte nuclear factor 4{alpha} and mediates protective effects of vitamin D in nonalcoholic fatty liver disease [Metabolism] |
Hong Zhang, Zhe Shen, Yiming Lin, Jie Zhang, Yuwei Zhang, Peihao Liu, Hang Zeng, Mengli Yu, Xueyang Chen, Longgui Ning, Xinli Mao, Li Cen, Chaohui Yu, Chengfu Xu |
|
| 2020-03-20 |
Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis [Protein Structure and Folding] |
Ghader Bashiri, Laura V. Nigon, Ehab N. M. Jirgis, Ngoc Anh Thu Ho, Tamsyn Stanborough, Stephanie S. Dawes, Edward N. Baker, Esther M. M. Bulloch, Jodie M. Johnston |
|
| 2020-03-20 |
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload [Metabolism] |
Aaron M. Wortham, Devorah C. Goldman, Juxing Chen, William H. Fleming, An-Sheng Zhang, Caroline A. Enns |
|
| 2020-03-20 |
The regulatory protein 14-3-3{beta} binds to the IQ motifs of myosin-IC independent of phosphorylation [Cell Biology] |
Huan-Hong Ji, E. Michael Ostap |
|
| 2020-03-13 |
Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity [Protein Structure and Folding] |
Chia-Yu Kang, I-Hsiu Huang, Chi-Chi Chou, Tsai-Yu Wu, Jyun-Cyuan Chang, Yu-Yuan Hsiao, Cheng-Hsuan Cheng, Wei-Jiun Tsai, Kai-Cheng Hsu, Shuying Wang |
|
| 2020-03-13 |
Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. [Additions and Corrections] |
Maura Poli, Ferdous Anower-E-Khuda, Michela Asperti, Paola Ruzzenenti, Magdalena Gryzik, Andrea Denardo, Philip L. S. M. Gordts, Paolo Arosio, Jeffrey D. Esko |
|
| 2020-03-13 |
Galectin 3-binding protein suppresses amyloid-{beta} production by modulating {beta}-cleavage of amyloid precursor protein [Neurobiology] |
Tsuneyoshi Seki, Motoi Kanagawa, Kazuhiro Kobayashi, Hisatomo Kowa, Naoki Yahata, Kei Maruyama, Nobuhisa Iwata, Haruhisa Inoue, Tatsushi Toda |
|
| 2020-03-13 |
Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode [Plant Biology] |
David A. Korasick, Pramod K. Kandoth, John J. Tanner, Melissa G. Mitchum, Lesa J. Beamer |
|
| 2020-03-13 |
The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents [Molecular Biophysics] |
Yu Xu, Lucas Cantwell, Andrei I. Molosh, Leigh D. Plant, Dimitris Gazgalis, Stephanie D. Fitz, Erik T. Dustrude, Yuchen Yang, Takeharu Kawano, Sumanta Garai, Sami F. Noujaim, Anantha Shekhar, Diomedes E. Logothetis, Ganesh A. Thakur |
|
| 2020-03-13 |
Rab35-GEFs, DENND1A and folliculin differentially regulate podocalyxin trafficking in two- and three-dimensional epithelial cell cultures [Membrane Biology] |
Riko Kinoshita, Yuta Homma, Mitsunori Fukuda |
|
| 2020-03-13 |
Generation and validation of a PITX2-EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells [Methods and Resources] |
Toru Okubo, Ryuhei Hayashi, Shun Shibata, Yuji Kudo, Yuki Ishikawa, Saki Inoue, Yuki Kobayashi, Ai Honda, Yoichi Honma, Satoshi Kawasaki, Kohji Nishida |
|
| 2020-03-13 |
Opposing effects of polysulfides and thioredoxin on apoptosis through caspase persulfidation [Signal Transduction] |
Ilana Braunstein, Rotem Engelman, Ofer Yitzhaki, Tamar Ziv, Erwan Galardon, Moran Benhar |
|
| 2020-03-13 |
Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 [Cell Biology] |
Xiaoyun Wu, Gavin R. Schnitzler, Galen F. Gao, Brett Diamond, Andrew R. Baker, Bethany Kaplan, Kaylyn Williamson, Lindsay Westlake, Selena Lorrey, Timothy A. Lewis, Colin W. Garvie, Martin Lange, Sikander Hayat, Henrik Seidel, John Doench, Andrew D. Chern |
|
| 2020-03-13 |
Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation [Enzymology] |
Vanda Toldi, Andras Szabo, Miklos Sahin–Toth |
|
| 2020-03-13 |
Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products [Microbiology] |
Jitka Petrlova, Ganna Petruk, Roland G. Huber, Eilish W. McBurnie, Mariena J. A. van der Plas, Peter J. Bond, Manoj Puthia, Artur Schmidtchen |
|
| 2020-03-13 |
A moonlighting nuclease puts CRISPR in its place [Enzymology] |
C. Martin Lawrence |
|
| 2020-03-13 |
Processing and integration of functionally oriented prespacers in the Escherichia coli CRISPR system depends on bacterial host exonucleases [DNA and Chromosomes] |
Anita Ramachandran, Lesley Summerville, Brian A. Learn, Lily DeBell, Scott Bailey |
|
| 2020-03-13 |
A potential new target for autoinflammatory bone disease [Cell Biology] |
Elizabeth L. Hartland |
|
| 2020-03-13 |
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease [Protein Structure and Folding] |
Raniki Kumari, Roshan Kumar, Sanjay Kumar, Abhishek Kumar Singh, Pranita Hanpude, Deepak Jangir, Tushar Kanti Maiti |
|
| 2020-03-13 |
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth [Protein Synthesis and Degradation] |
Xue Li, Lingmei Kong, Qihong Yang, Aizhu Duan, Xiaoman Ju, Bicheng Cai, Lin Chen, Tao An, Yan Li |
|
| 2020-03-13 |
Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-{kappa}B and expression of the long-noncoding RNA HAS2-AS1 [Cell Biology] |
Ilaria Caon, Barbara Bartolini, Paola Moretto, Arianna Parnigoni, Elena Carava, Daiana L. Vitale, Laura Alaniz, Manuela Viola, Evgenia Karousou, Giancarlo De Luca, Vincent C. Hascall, Alberto Passi, Davide Vigetti |
|
| 2020-03-13 |
Loss of the voltage-gated proton channel Hv1 decreases insulin secretion and leads to hyperglycemia and glucose intolerance in mice [Metabolism] |
Huimin Pang, Xudong Wang, Shiqun Zhao, Wang Xi, Jili Lv, Jiwei Qin, Qing Zhao, Yongzhe Che, Liangyi Chen, Shu Jie Li |
|
| 2020-03-13 |
A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing in vitro [Plant Biology] |
Michael L. Hayes, Paola I. Santibanez |
|
| 2020-03-13 |
A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus [Cell Biology] |
Ambra A. Grolla, Riccardo Miggiano, Daniele Di Marino, Michele Bianchi, Alessandro Gori, Giuseppe Orsomando, Federica Gaudino, Ubaldina Galli, Erika Del Grosso, Francesca Mazzola, Carlo Angeletti, Martina Guarneri, Simone Torretta, Marta Calabro, Sara Bou |
|
| 2020-03-13 |
Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments [Protein Structure and Folding] |
Jordan M. Mancl, Cristian Suarez, Wenguang G. Liang, David R. Kovar, Wei-Jen Tang |
|
| 2020-03-13 |
Methionine sulfoxide reductase B from Corynebacterium diphtheriae catalyzes sulfoxide reduction via an intramolecular disulfide cascade [Protein Structure and Folding] |
Maria–Armineh Tossounian, Anh–Co Khanh Truong, Lieven Buts, Khadiȷa Wahni, Alvaro Mourenza, Martine Leermakers, Didier Vertommen, Luis Mariano Mateos, Alexander N. Volkov, Joris Messens |
|
| 2020-03-13 |
A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude [Gene Regulation] |
Yagmur Umay Doruk, Darya Yarparvar, Yasemin Kubra Akyel, Seref Gul, Ali Cihan Taskin, Fatma Yilmaz, Ibrahim Baris, Nuri Ozturk, Metin Turkay, Narin Ozturk, Alper Okyar, Ibrahim Halil Kavakli |
|
| 2020-03-13 |
The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites [Molecular Bases of Disease] |
Alan G. Raetz, Douglas M. Banda, Xiaoyan Ma, Gege Xu, Anisha N. Rajavel, Paige L. McKibbin, Carlito B. Lebrilla, Sheila S. David |
|
| 2020-03-13 |
Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKK{gamma} protein enhances the anticancer effect of chemotherapy [Signal Transduction] |
Jaganathan Venkatesh, Sreeja C. Sekhar, Vino T. Cheriyan, Magesh Muthu, Paul Meister, Edi Levi, Sijana Dzinic, James W. Gauld, Lisa A. Polin, Arun K. Rishi |
|
| 2020-03-13 |
Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain [Cell Biology] |
Fajr A. Aleisa, Kosuke Sakashita, Jae Man Lee, Dina B. AbuSamra, Bader Al Alwan, Shuho Nozue, Muhammad Tehseen, Samir M. Hamdan, Satoshi Habuchi, Takahiro Kusakabe, Jasmeen S. Merzaban |
|
| 2020-03-13 |
Histone methyltransferase G9a diminishes expression of cannabinoid CB1 receptors in primary sensory neurons in neuropathic pain [Neurobiology] |
Yi Luo, Jixiang Zhang, Lin Chen, Shao-Rui Chen, Hong Chen, Guangfen Zhang, Hui-Lin Pan |
|
| 2020-03-13 |
Correction: Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation. [Additions and Corrections] |
Tatiana Fila, Stefania Trazzi, Christophe Crochemore, Renata Bartesaghi, Elisabetta Ciani |
|
| 2020-03-13 |
A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2) [Enzymology] |
Zachary Hartman, Werner J. Geldenhuys, Yehenew M. Agazie |
|
| 2020-03-13 |
Correction: Glycosylation alters dimerization properties of a cell-surface signaling protein, carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). [Additions and Corrections] |
You Zhuo, Jeong-Yeh Yang, Kelley W. Moremen, James H. Prestegard |
|
| 2020-03-13 |
The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis [Signal Transduction] |
Tejasvi K. Dasari, Rechel Geiger, Rajendra Karki, Balaji Banoth, Bhesh Raj Sharma, Prajwal Gurung, Amanda Burton, Thirumala-Devi Kanneganti |
|
| 2020-02-25 |
Molecular basis for activation and biased signaling at the thrombin-activated GPCR proteinase activated receptor-4 (PAR4) [Cell Biology] |
Pierre E. Thibeault, Jordan C. LeSarge, D'Arcy Arends, Michaela Fernandes, Peter Chidiac, Peter B. Stathopulos, Leonard G. Luyt, Rithwik Ramachandran |
|
| 2020-02-25 |
The topology of the ER-resident phospholipid methyltransferase Opi3 of Saccharomyces cerevisiae is consistent with in trans catalysis [Membrane Biology] |
Grzegorz Pawlik, Mike F. Renne, Matthijs A. Kol, Anton I. P. M. de Kroon |
|
| 2020-02-25 |
Cell adhesion in cancer: Beyond the migration of single cells [Signal Transduction] |
Michalina Janiszewska, Marina Candido Primi, Tina Izard |
|
| 2020-02-25 |
Drosophila ELYS regulates Dorsal dynamics during development [Cell Biology] |
Saurabh Jayesh Kumar Mehta, Vimlesh Kumar, Ram Kumar Mishra |
|
| 2020-02-25 |
Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I [Enzymology] |
Shinpei Uno, Takahiro Masuya, Kyoko Shinzawa-Itoh, Jonathan Lasham, Outi Haapanen, Tomoo Shiba, Daniel Ken Inaoka, Vivek Sharma, Masatoshi Murai, Hideto Miyoshi |
|
| 2020-02-25 |
The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy [Neurobiology] |
Anastasia C. Murthy, Nicolas L. Fawzi |
|
| 2020-02-25 |
An in vivo study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system [Gene Regulation] |
Stefania Musilli, Vincent Abramowski, Benoit Roch, Jean-Pierre de Villartay |
|
| 2020-02-25 |
Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway [Signal Transduction] |
Jeoung-Eun Park, David D. Brand, Edward F. Rosloniec, Ae-Kyung Yi, John M. Stuart, Andrew H. Kang, Linda K. Myers |
|
| 2020-02-25 |
Estrogen-induced FOS-like 1 regulates matrix metalloproteinase expression and the motility of human endometrial and decidual stromal cells [Cell Biology] |
Chao Chen, Congcong Li, Weichun Liu, Feng Guo, Xi Kou, Si Sun, Taiyang Ye, Shanji Li, Aimin Zhao |
|
| 2020-02-25 |
A fluorescence-activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques [Microbiology] |
Jorge L. Arias–Arias, Derek J. MacPherson, Maureen E. Hill, Jeanne A. Hardy, Rodrigo Mora–Rodriguez |
|
| 2020-02-25 |
Steric constraints control processing of glycosylphosphatidylinositol anchors in Trypanosoma brucei [Microbiology] |
Carolina M. Koeller, Calvin Tiengwe, Kevin J. Schwartz, James D. Bangs |
|
| 2020-02-25 |
Tyrosine nitration on calmodulin enhances calcium-dependent association and activation of nitric-oxide synthase [Molecular Bases of Disease] |
Joseph J. Porter, Hyo Sang Jang, Mohammad Mahfuzul Haque, Dennis J. Stuehr, Ryan A. Mehl |
|
| 2020-02-25 |
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage [Molecular Bases of Disease] |
Parker G. Jobin, Nestor Solis, Yoan Machado, Peter A. Bell, Simran K. Rai, Nam Hoon Kwon, Sunghoon Kim, Christopher M. Overall, Georgina S. Butler |
|
| 2020-02-25 |
Nogo BACE jumps on the exosome [Cell Biology] |
Sienna Drake, Alyson Fournier |
|
| 2020-02-25 |
Correction: Cultivation at high osmotic pressure confers ubiquinone 8-independent protection of respiration on Escherichia coli. [Additions and Corrections] |
Laura Tempelhagen, Anita Ayer, Doreen E. Culham, Roland Stocker, Janet M. Wood |
|
| 2020-02-25 |
Interaction between the yeast RAVE complex and Vph1-containing Vo sectors is a central glucose-sensitive interaction required for V-ATPase reassembly [Cell Biology] |
Michael C. Jaskolka, Patricia M. Kane |
|
| 2020-02-25 |
A proteolytic C-terminal fragment of Nogo-A (reticulon-4A) is released in exosomes and potently inhibits axon regeneration [Cell Biology] |
Yuichi Sekine, Jane A. Lindborg, Stephen M. Strittmatter |
|
| 2020-02-25 |
DAPLE protein inhibits nucleotide exchange on G{alpha}s and G{alpha}q via the same motif that activates G{alpha}i [Signal Transduction] |
Arthur Marivin, Marcin Maziarz, Jingyi Zhao, Vincent DiGiacomo, Isabel Olmos Calvo, Emily A. Mann, Jason Ear, Juan B. Blanco-Canosa, Elliott M. Ross, Pradipta Ghosh, Mikel Garcia-Marcos |
|
| 2020-02-25 |
The location of sensing determines the pancreatic {beta}-cell response to the viral mimetic dsRNA [Molecular Bases of Disease] |
Zachary R. Shaheen, Joshua D. Stafford, Michael G. Voss, Bryndon J. Oleson, Jennifer S. Stancill, John A. Corbett |
|
| 2020-02-25 |
A transient amphipathic helix in the prodomain of PCSK9 facilitates binding to low-density lipoprotein particles [Molecular Bases of Disease] |
Samantha K. Sarkar, Alexander C. Y. Foo, Angela Matyas, Ikhuosho Asikhia, Tanja Kosenko, Natalie K. Goto, Ariela Vergara-Jaque, Thomas A. Lagace |
|
| 2020-02-25 |
Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling [Signal Transduction] |
Nicholas J. Cope, Borna Novak, Zhiwei Liu, Maria Cavallo, Amber Y. Gunderwala, Matthew Connolly, Zhihong Wang |
|
| 2020-02-25 |
Functional interactions between gyrase subunits are optimized in a species-specific manner [Molecular Biophysics] |
Daniela Weidlich, Dagmar Klostermeier |
|
| 2020-02-25 |
Protein secondary structure determines the temporal relationship between folding and disulfide formation [Cell Biology] |
Philip J. Robinson, Shingo Kanemura, Xiaofei Cao, Neil J. Bulleid |
|
| 2020-02-25 |
Piece by piece: Building a ribozyme [Enzymology] |
Michael W. Gray, Venkat Gopalan |
|
| 2020-02-25 |
Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody [Protein Synthesis and Degradation] |
Amir S. Razai, Brendan P. Eckelman, Guy S. Salvesen |
|
| 2020-02-25 |
The retina and retinal pigment epithelium differ in nitrogen metabolism and are metabolically connected [Neurobiology] |
Rong Xu, Brianna K. Ritz, Yekai Wang, Jiancheng Huang, Chen Zhao, Kaizheng Gong, Xinnong Liu, Jianhai Du |
|
| 2020-02-25 |
HYBID (alias KIAA1199/CEMIP) and hyaluronan synthase coordinately regulate hyaluronan metabolism in histamine-stimulated skin fibroblasts [Glycobiology and Extracellular Matrices] |
Hiroyuki Yoshida, Mika Aoki, Aya Komiya, Yoko Endo, Keigo Kawabata, Tomomi Nakamura, Shingo Sakai, Tetsuya Sayo, Yasunori Okada, Yoshito Takahashi |
|
| 2020-02-25 |
Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K) [Cell Biology] |
Sun-Hong Hwang, Sunhoe Bang, Wonho Kim, Jongkyeong Chung |
|
| 2020-02-25 |
Granulins modulate liquid-liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43 [Molecular Bases of Disease] |
Anukool A. Bhopatkar, Vladimir N. Uversky, Vijayaraghavan Rangachari |
|
| 2020-02-25 |
Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer [Molecular Bases of Disease] |
Xianzhou Song, Hironari Akasaka, Hua Wang, Reza Abbasgholizadeh, Ji-Hyun Shin, Fenglin Zang, Jiayi Chen, Craig D. Logsdon, Anirban Maitra, Andrew J. Bean, Huamin Wang |
|
| 2020-02-25 |
Correction: Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation. [Additions and Corrections] |
Kushagra Bansal, Kithiganahalli N. Balaji |
|
| 2020-02-25 |
Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells [Genomics and Proteomics] |
Ian M. McDonald, Gavin D. Grant, Michael P. East, Thomas S. K. Gilbert, Emily M. Wilkerson, Dennis Goldfarb, Joshua Beri, Laura E. Herring, Cyrus Vaziri, Jeanette Gowen Cook, Michael J. Emanuele, Lee M. Graves |
|
| 2020-02-25 |
Withdrawal: Outer membrane protein A (OmpA) of Shigella flexneri 2a links innate and adaptive immunity in a TLR2-dependent manner and involvement of IL-12 and nitric oxide. [Withdrawals/Retractions] |
Debasis Pore, Nibedita Mahata, Manoj K. Chakrabarti |
|
| 2020-02-25 |
Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding [Protein Structure and Folding] |
Julia Mader, Jessica Huber, Florian Bonn, Volker Dotsch, Vladimir V. Rogov, Anȷa Bremm |
|
| 2020-02-14 |
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation [Signal Transduction] |
Cristina Azevedo, Yann Desfougeres, Yannasittha Jiramongkol, Hamish Partington, Sasanan Trakansuebkul, Jyoti Singh, Nicole Steck, Henning J. Jessen, Adolfo Saiardi |
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| 2020-02-14 |
Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist [Membrane Biology] |
Caleigh M. Azumaya, Emily A. Linton, Caitlin J. Risener, Terunaga Nakagawa, Erkan Karakas |
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| 2020-02-14 |
Correction: Protochromic absorption changes in the two-cysteine photocycle of a blue/orange cyanobacteriochrome. [Additions and Corrections] |
Teppei Sato, Takashi Kikukawa, Risako Miyoshi, Kousuke Kajimoto, Chinatsu Yonekawa, Tomotsumi Fujisawa, Masashi Unno, Toshihiko Eki, Yuu Hirose |
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| 2020-02-14 |
A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation [Microbiology] |
Melissanne de Wispelaere, Margot Carocci, Dominique J. Burri, William J. Neidermyer Jr., Calla M. Olson, Imme Roggenbach, Yanke Liang, Jinhua Wang, Sean P. J. Whelan, Nathanael S. Gray, Priscilla L. Yang |
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| 2020-02-14 |
The mitochondrial iron exporter genes MMT1 and MMT2 in yeast are transcriptionally regulated by Aft1 and Yap1 [Cell Biology] |
Liangtao Li, Sophie Bertram, Jerry Kaplan, Xuan Jia, Diane M. Ward |
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| 2020-02-14 |
The bacterial deubiquitinase Ceg23 regulates the association of Lys-63-linked polyubiquitin molecules on the Legionella phagosome [Cell Biology] |
Kelong Ma, Xiangkai Zhen, Biao Zhou, Ninghai Gan, Yang Cao, Chengpeng Fan, Songying Ouyang, Zhao-Qing Luo, Jiazhang Qiu |
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